Dragmacidin e synthesis studies. Preparation of a model heptacyclic core structure

Ken S. Feldman, Paiboon Ngernmeesri

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

The conversion of a cycloheptannelated indole platform into the heptacyclic core structure of dragmacidin E proceeded over nine steps. Key sequences include a cyclocondensation to form an intermediate dihydropyrazinone ring and the conversion of a cyclic urea into the cyclic guanidine of the target.

Original languageEnglish (US)
Pages (from-to)4502-4505
Number of pages4
JournalOrganic Letters
Volume12
Issue number20
DOIs
StatePublished - Oct 15 2010

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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