TY - GEN
T1 - Dynamic analysis of a spread cell using finite element method
AU - Wee, Hwabok
AU - Voloshin, Arkady
PY - 2014
Y1 - 2014
N2 - The dynamic analysis of a cultured cell using Finite Element Analysis is presented to understand the effect of vibration on a cell structure. The model of a spread cell on a culturing plate has been developed as a continuum model and a cellular tensegrity model. Using Finite Element modal analysis, natural frequencies and mode shapes of both models were obtained and compared with each other. Finite Element harmonic response analysis was carried out to investigate the dynamic response of a spread cell exposed to vibration in the frequency range of 1-60 Hz with 1 G acceleration. Both continuum model and tensegrity model showed that the first three natural frequencies appeared in range of 18 ∼ 27 Hz and they were in the effective vibration frequency range for bone cell growth. In mode 1-3 the major oscillation was observed in horizontal direction and the resonance occurred when the base vibration frequency was closed to the calculated natural frequency. It is presumed that the optimal frequency for bone cell growth is closely related the natural frequency of cell structures and associated with the resonance of cellular structures. For better understanding resonance of cell structure future studies will consider the damping capability of cell structures.
AB - The dynamic analysis of a cultured cell using Finite Element Analysis is presented to understand the effect of vibration on a cell structure. The model of a spread cell on a culturing plate has been developed as a continuum model and a cellular tensegrity model. Using Finite Element modal analysis, natural frequencies and mode shapes of both models were obtained and compared with each other. Finite Element harmonic response analysis was carried out to investigate the dynamic response of a spread cell exposed to vibration in the frequency range of 1-60 Hz with 1 G acceleration. Both continuum model and tensegrity model showed that the first three natural frequencies appeared in range of 18 ∼ 27 Hz and they were in the effective vibration frequency range for bone cell growth. In mode 1-3 the major oscillation was observed in horizontal direction and the resonance occurred when the base vibration frequency was closed to the calculated natural frequency. It is presumed that the optimal frequency for bone cell growth is closely related the natural frequency of cell structures and associated with the resonance of cellular structures. For better understanding resonance of cell structure future studies will consider the damping capability of cell structures.
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U2 - 10.1007/978-3-319-00777-9_19
DO - 10.1007/978-3-319-00777-9_19
M3 - Conference contribution
AN - SCOPUS:84886815112
SN - 9783319007762
T3 - Conference Proceedings of the Society for Experimental Mechanics Series
SP - 135
EP - 140
BT - Mechanics of Biological Systems and Materials - Proceedings of the 2013 Annual Conference on Experimental and Applied Mechanics
T2 - 2013 Annual Conference on Experimental and Applied Mechanics
Y2 - 3 June 2013 through 5 June 2013
ER -