Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States

A. K. Pradhan, J. S. van Kessel, J. S. Karns, D. R. Wolfgang, Ernest Peter Hovingh, K. A. Nelen, J. M. Smith, R. H. Whitlock, T. Fyock, S. Ladely, P. J. Fedorka-Cray, Y. H. Schukken

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Abstract

Endemic infectious diseases in dairy cattle are of significant concern to the industry as well as for public health because of their potential impact on animal and human health, milk and meat production, food safety, and economics. We sought to provide insight into the dynamics of important endemic infectious diseases in 3 northeastern US dairy herds. Fecal samples from individual cows and various environmental samples from these farms were tested for the presence of major zoonotic pathogens (i.e., Salmonella, Campylobacter, and Listeria) as well as commensal bacteria Escherichia coli and enterococci. Additionally, the presence of Mycobacterium avium ssp. paratuberculosis was tested in fecal and serum samples from individual cows. Test results and health and reproductive records were maintained in a database, and fecal, plasma, DNA, and tissue samples were kept in a biobank. All bacteria of interest were detected on these farms and their presence was variable both within and between farms. The prevalence of Listeria spp. and L. monocytogenes in individual fecal samples within farm A ranged from 0 to 68.2% and 0 to 25.5%, respectively, over a period of 3 yr. Within farm B, continuous fecal shedding of Salmonella spp. was observed with a prevalence ranging from 8 to 88%; Salmonella Cerro was the predominant serotype. Farm C appeared less contaminated with Salmonella and Listeria, although in the summer of 2005, 50 and 19.2% of fecal samples were positive for Listeria and L. monocytogenes, respectively. The high prevalence of E. coli (89 to 100%), Enterococcus (75 to 100%), and Campylobacter (0 to 81%) in feces suggested they were ubiquitous throughout the farm environment. Fecal culture and ELISA results indicated a low prevalence of Mycobacterium avium ssp. paratuberculosis infection in these farms (0 to 13.6% and 0 to 4.9% for culture-positive and ELISA-positive, respectively), although the occasional presence of high shedders was observed. Results have major implications for food safety and epidemiology by providing a better understanding of infectious disease dynamics on dairy farms. Comprehensive understanding of these infections may lead to better farm management practices and pathogen reduction programs to control and reduce the on-farm contamination of these pathogens and to prevent their further entry into the food-chain.

Original languageEnglish (US)
Pages (from-to)1811-1825
Number of pages15
JournalJournal of Dairy Science
Volume92
Issue number4
DOIs
StatePublished - Jan 1 2009

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Endemic Diseases
New England
Northeastern United States
dairy herds
infectious diseases
Communicable Diseases
farms
Listeria
animals
Salmonella
Mycobacterium avium
Paratuberculosis
paratuberculosis
Enterococcus
Campylobacter
sampling
Food Safety
Listeria monocytogenes
food safety
pathogens

All Science Journal Classification (ASJC) codes

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

Pradhan, A. K. ; van Kessel, J. S. ; Karns, J. S. ; Wolfgang, D. R. ; Hovingh, Ernest Peter ; Nelen, K. A. ; Smith, J. M. ; Whitlock, R. H. ; Fyock, T. ; Ladely, S. ; Fedorka-Cray, P. J. ; Schukken, Y. H. / Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States. In: Journal of Dairy Science. 2009 ; Vol. 92, No. 4. pp. 1811-1825.
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abstract = "Endemic infectious diseases in dairy cattle are of significant concern to the industry as well as for public health because of their potential impact on animal and human health, milk and meat production, food safety, and economics. We sought to provide insight into the dynamics of important endemic infectious diseases in 3 northeastern US dairy herds. Fecal samples from individual cows and various environmental samples from these farms were tested for the presence of major zoonotic pathogens (i.e., Salmonella, Campylobacter, and Listeria) as well as commensal bacteria Escherichia coli and enterococci. Additionally, the presence of Mycobacterium avium ssp. paratuberculosis was tested in fecal and serum samples from individual cows. Test results and health and reproductive records were maintained in a database, and fecal, plasma, DNA, and tissue samples were kept in a biobank. All bacteria of interest were detected on these farms and their presence was variable both within and between farms. The prevalence of Listeria spp. and L. monocytogenes in individual fecal samples within farm A ranged from 0 to 68.2{\%} and 0 to 25.5{\%}, respectively, over a period of 3 yr. Within farm B, continuous fecal shedding of Salmonella spp. was observed with a prevalence ranging from 8 to 88{\%}; Salmonella Cerro was the predominant serotype. Farm C appeared less contaminated with Salmonella and Listeria, although in the summer of 2005, 50 and 19.2{\%} of fecal samples were positive for Listeria and L. monocytogenes, respectively. The high prevalence of E. coli (89 to 100{\%}), Enterococcus (75 to 100{\%}), and Campylobacter (0 to 81{\%}) in feces suggested they were ubiquitous throughout the farm environment. Fecal culture and ELISA results indicated a low prevalence of Mycobacterium avium ssp. paratuberculosis infection in these farms (0 to 13.6{\%} and 0 to 4.9{\%} for culture-positive and ELISA-positive, respectively), although the occasional presence of high shedders was observed. Results have major implications for food safety and epidemiology by providing a better understanding of infectious disease dynamics on dairy farms. Comprehensive understanding of these infections may lead to better farm management practices and pathogen reduction programs to control and reduce the on-farm contamination of these pathogens and to prevent their further entry into the food-chain.",
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Pradhan, AK, van Kessel, JS, Karns, JS, Wolfgang, DR, Hovingh, EP, Nelen, KA, Smith, JM, Whitlock, RH, Fyock, T, Ladely, S, Fedorka-Cray, PJ & Schukken, YH 2009, 'Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States', Journal of Dairy Science, vol. 92, no. 4, pp. 1811-1825. https://doi.org/10.3168/jds.2008-1486

Dynamics of endemic infectious diseases of animal and human importance on three dairy herds in the northeastern United States. / Pradhan, A. K.; van Kessel, J. S.; Karns, J. S.; Wolfgang, D. R.; Hovingh, Ernest Peter; Nelen, K. A.; Smith, J. M.; Whitlock, R. H.; Fyock, T.; Ladely, S.; Fedorka-Cray, P. J.; Schukken, Y. H.

In: Journal of Dairy Science, Vol. 92, No. 4, 01.01.2009, p. 1811-1825.

Research output: Contribution to journalArticle

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AU - Schukken, Y. H.

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N2 - Endemic infectious diseases in dairy cattle are of significant concern to the industry as well as for public health because of their potential impact on animal and human health, milk and meat production, food safety, and economics. We sought to provide insight into the dynamics of important endemic infectious diseases in 3 northeastern US dairy herds. Fecal samples from individual cows and various environmental samples from these farms were tested for the presence of major zoonotic pathogens (i.e., Salmonella, Campylobacter, and Listeria) as well as commensal bacteria Escherichia coli and enterococci. Additionally, the presence of Mycobacterium avium ssp. paratuberculosis was tested in fecal and serum samples from individual cows. Test results and health and reproductive records were maintained in a database, and fecal, plasma, DNA, and tissue samples were kept in a biobank. All bacteria of interest were detected on these farms and their presence was variable both within and between farms. The prevalence of Listeria spp. and L. monocytogenes in individual fecal samples within farm A ranged from 0 to 68.2% and 0 to 25.5%, respectively, over a period of 3 yr. Within farm B, continuous fecal shedding of Salmonella spp. was observed with a prevalence ranging from 8 to 88%; Salmonella Cerro was the predominant serotype. Farm C appeared less contaminated with Salmonella and Listeria, although in the summer of 2005, 50 and 19.2% of fecal samples were positive for Listeria and L. monocytogenes, respectively. The high prevalence of E. coli (89 to 100%), Enterococcus (75 to 100%), and Campylobacter (0 to 81%) in feces suggested they were ubiquitous throughout the farm environment. Fecal culture and ELISA results indicated a low prevalence of Mycobacterium avium ssp. paratuberculosis infection in these farms (0 to 13.6% and 0 to 4.9% for culture-positive and ELISA-positive, respectively), although the occasional presence of high shedders was observed. Results have major implications for food safety and epidemiology by providing a better understanding of infectious disease dynamics on dairy farms. Comprehensive understanding of these infections may lead to better farm management practices and pathogen reduction programs to control and reduce the on-farm contamination of these pathogens and to prevent their further entry into the food-chain.

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