EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

Luca Giovanella, Anca M. Avram, Ioannis Iakovou, Jennifer Kwak, Susan A. Lawson, Elizabeth Lulaj, Markus Luster, Arnoldo Piccardo, Matthias Schmidt, Mark Tulchinsky, Frederick A. Verburg, Ely Wolin

Research output: Contribution to journalArticle

Abstract

Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

Original languageEnglish (US)
Pages (from-to)2514-2525
Number of pages12
JournalEuropean Journal of Nuclear Medicine and Molecular Imaging
Volume46
Issue number12
DOIs
StatePublished - Nov 1 2019

Fingerprint

Molecular Imaging
Nuclear Medicine
Practice Guidelines
Radionuclide Imaging
Thyroid Gland
Radiopharmaceuticals
Hyperthyroidism
Iodine
Thyroid Dysgenesis
Sodium Pertechnetate Tc 99m
Choristoma
Thyroid Nodule
Thyrotoxicosis
Thyroid Diseases
Iodides
Positron-Emission Tomography
Joints

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Giovanella, L., Avram, A. M., Iakovou, I., Kwak, J., Lawson, S. A., Lulaj, E., ... Wolin, E. (2019). EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy. European Journal of Nuclear Medicine and Molecular Imaging, 46(12), 2514-2525. https://doi.org/10.1007/s00259-019-04472-8
Giovanella, Luca ; Avram, Anca M. ; Iakovou, Ioannis ; Kwak, Jennifer ; Lawson, Susan A. ; Lulaj, Elizabeth ; Luster, Markus ; Piccardo, Arnoldo ; Schmidt, Matthias ; Tulchinsky, Mark ; Verburg, Frederick A. ; Wolin, Ely. / EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy. In: European Journal of Nuclear Medicine and Molecular Imaging. 2019 ; Vol. 46, No. 12. pp. 2514-2525.
@article{8efd2b8a135446a9a3e6a738ce9de5a1,
title = "EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy",
abstract = "Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.",
author = "Luca Giovanella and Avram, {Anca M.} and Ioannis Iakovou and Jennifer Kwak and Lawson, {Susan A.} and Elizabeth Lulaj and Markus Luster and Arnoldo Piccardo and Matthias Schmidt and Mark Tulchinsky and Verburg, {Frederick A.} and Ely Wolin",
year = "2019",
month = "11",
day = "1",
doi = "10.1007/s00259-019-04472-8",
language = "English (US)",
volume = "46",
pages = "2514--2525",
journal = "European Journal of Nuclear Medicine and Molecular Imaging",
issn = "1619-7070",
publisher = "Springer Verlag",
number = "12",

}

Giovanella, L, Avram, AM, Iakovou, I, Kwak, J, Lawson, SA, Lulaj, E, Luster, M, Piccardo, A, Schmidt, M, Tulchinsky, M, Verburg, FA & Wolin, E 2019, 'EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy', European Journal of Nuclear Medicine and Molecular Imaging, vol. 46, no. 12, pp. 2514-2525. https://doi.org/10.1007/s00259-019-04472-8

EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy. / Giovanella, Luca; Avram, Anca M.; Iakovou, Ioannis; Kwak, Jennifer; Lawson, Susan A.; Lulaj, Elizabeth; Luster, Markus; Piccardo, Arnoldo; Schmidt, Matthias; Tulchinsky, Mark; Verburg, Frederick A.; Wolin, Ely.

In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 46, No. 12, 01.11.2019, p. 2514-2525.

Research output: Contribution to journalArticle

TY - JOUR

T1 - EANM practice guideline/SNMMI procedure standard for RAIU and thyroid scintigraphy

AU - Giovanella, Luca

AU - Avram, Anca M.

AU - Iakovou, Ioannis

AU - Kwak, Jennifer

AU - Lawson, Susan A.

AU - Lulaj, Elizabeth

AU - Luster, Markus

AU - Piccardo, Arnoldo

AU - Schmidt, Matthias

AU - Tulchinsky, Mark

AU - Verburg, Frederick A.

AU - Wolin, Ely

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

AB - Introduction: Scintigraphic evaluation of the thyroid gland enables determination of the iodine-123 iodide or the 99mTc-pertechnetate uptake and distribution and remains the most accurate method for the diagnosis and quantification of thyroid autonomy and the detection of ectopic thyroid tissue. In addition, thyroid scintigraphy and radioiodine uptake test are useful to discriminate hyperthyroidism from destructive thyrotoxicosis and iodine-induced hyperthyroidism, respectively. Methods: Several radiopharmaceuticals are available to help in differentiating benign from malignant cytologically indeterminate thyroid nodules and for supporting clinical decision-making. This joint practice guideline/procedure standard from the European Association of Nuclear Medicine (EANM) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) provides recommendations based on the available evidence in the literature. Conclusion: The purpose of this practice guideline/procedure standard is to assist imaging specialists and clinicians in recommending, performing, and interpreting the results of thyroid scintigraphy (including positron emission tomography) with various radiopharmaceuticals and radioiodine uptake test in patients with different thyroid diseases.

UR - http://www.scopus.com/inward/record.url?scp=85070282839&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85070282839&partnerID=8YFLogxK

U2 - 10.1007/s00259-019-04472-8

DO - 10.1007/s00259-019-04472-8

M3 - Article

C2 - 31392371

AN - SCOPUS:85070282839

VL - 46

SP - 2514

EP - 2525

JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

SN - 1619-7070

IS - 12

ER -