TY - JOUR
T1 - Early androgen effects on aggression in children and adults with congenital adrenal hyperplasia
AU - Berenbaum, Sheri A.
AU - Resnick, Susan M.
N1 - Funding Information:
Acknowledgements: This research was supported in part by National Institutes of Health Grant HD19644. Some of the data from Sample 2 were collected as part of a collaborative project with Dr. Melissa Hines. We thank the tollowing people who contributed to the project: Drs. Stephen Duck, Orville Green, David Klein, Ora Pescovitz. Gail Richards, Julio Santiago, and Robert Uhlstrom generously provided access to their patients and answered medical questions; Dr. Duck also rated genital virilization of CAH girls in Sample 3; Drs. Auke Tellegen, Irving Gottesman, and Thomas Bouchard provided advice and support in the design and analysis of the study involving subjects in Sample 1; Brenda Henderson, Elizabeth Snyder, Kim Ketterling, and Robyn Reed collected and processed data from subjects in Samples 2 or 3; Kristina Korman assisted in data scoring, analysis, and manuscript preparation; George Vineyard helped with data entry and scoring. Dr. Pauline Maki provided helpful comments on the paper. We are very grateful to the subjects and their parents for their participation in the study. Portions of this paper were presented at the Xlllth biennial meeting of the International Society for the Study of Behavioral Development. Amsterdam, July 1994.
PY - 1997/10
Y1 - 1997/10
N2 - Males are more likely than females to show aggressive behavior across species, ages, and situations, and these differences may be partly influenced by early hormones. We studied aggression in three samples of subjects with congenital adrenal hyperplasia (CAH), who were exposed to high levels of androgen in the prenatal and early postnatal periods. Controls were siblings and first cousins similar in age. In Sample 1, adolescents and adults completed the Multidimensional Personality Questionnaire (MPQ), which includes an Aggression scale. In Sample 2, adolescents and adults completed the MPQ and a paper-and-pencil version of Reinisch's Aggression Inventory. In Sample 3, parents rated the aggression of children aged 3-12, using a modification of Reinisch's Inventory. In all three samples, control males had higher aggression scores than control females. Further, as predicted, females with CAH had higher aggression than control females, but the difference was significant only in adolescents and adults. These results suggest that early androgens contribute to variability in human aggression.
AB - Males are more likely than females to show aggressive behavior across species, ages, and situations, and these differences may be partly influenced by early hormones. We studied aggression in three samples of subjects with congenital adrenal hyperplasia (CAH), who were exposed to high levels of androgen in the prenatal and early postnatal periods. Controls were siblings and first cousins similar in age. In Sample 1, adolescents and adults completed the Multidimensional Personality Questionnaire (MPQ), which includes an Aggression scale. In Sample 2, adolescents and adults completed the MPQ and a paper-and-pencil version of Reinisch's Aggression Inventory. In Sample 3, parents rated the aggression of children aged 3-12, using a modification of Reinisch's Inventory. In all three samples, control males had higher aggression scores than control females. Further, as predicted, females with CAH had higher aggression than control females, but the difference was significant only in adolescents and adults. These results suggest that early androgens contribute to variability in human aggression.
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U2 - 10.1016/S0306-4530(97)00049-8
DO - 10.1016/S0306-4530(97)00049-8
M3 - Article
C2 - 9373884
AN - SCOPUS:0030722387
SN - 0306-4530
VL - 22
SP - 505
EP - 515
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
IS - 7
ER -
