Early necrosis following concurrent Temodar and radiotherapy in patients with glioblastoma

Marc C. Chamberlain, Michael Glantz, Lisa Chalmers, Alixis Van Horn, Andrew E. Sloan

Research output: Contribution to journalArticlepeer-review

277 Scopus citations

Abstract

Concurrent temozolomide (TMZ) and radiotherapy is the new standard of care for patients with newly diagnosed glioblastoma. In 51 consecutive patients treated according to this regimen, 7 patients (14%) manifested surgically confirmed early necrosis without evidence of recurrent tumor. This observation suggests that daily TMZ may represent a potent radiosensitizing regimen.

Original languageEnglish (US)
Pages (from-to)81-83
Number of pages3
JournalJournal of neuro-oncology
Volume82
Issue number1
DOIs
StatePublished - Mar 1 2007

All Science Journal Classification (ASJC) codes

  • Oncology
  • Neurology
  • Clinical Neurology
  • Cancer Research

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