Economically viable efficient synthesis of (±)-methysticin: A component in kava potentially responsible for its cancer chemopreventive activity

Ahmad Ali Shaik, Jonathan Tan, Junxuan Lü, Chengguo Xing

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A highly efficient and green synthesis of (±)-methysticin was developed from inexpensive piperonal, requiring two extraction procedures and one chromatographic purification in the final step with 51% overall yield. This new method is superior compared to known literature procedures and is highly reproducible and scalable up to gram scale.

Original languageEnglish (US)
Pages (from-to)137-145
Number of pages9
JournalArkivoc
Volume2012
Issue number8
DOIs
StatePublished - Jun 29 2012

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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