Economically viable efficient synthesis of (±)-methysticin: A component in kava potentially responsible for its cancer chemopreventive activity

Ahmad Ali Shaik, Jonathan Tan, Junxuan Lü, Chengguo Xing

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A highly efficient and green synthesis of (±)-methysticin was developed from inexpensive piperonal, requiring two extraction procedures and one chromatographic purification in the final step with 51% overall yield. This new method is superior compared to known literature procedures and is highly reproducible and scalable up to gram scale.

Original languageEnglish (US)
Pages (from-to)137-145
Number of pages9
JournalArkivoc
Volume2012
Issue number8
DOIs
StatePublished - Jun 29 2012

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Purification
methysticin
piperonal

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

Cite this

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Economically viable efficient synthesis of (±)-methysticin : A component in kava potentially responsible for its cancer chemopreventive activity. / Ali Shaik, Ahmad; Tan, Jonathan; Lü, Junxuan; Xing, Chengguo.

In: Arkivoc, Vol. 2012, No. 8, 29.06.2012, p. 137-145.

Research output: Contribution to journalArticle

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AU - Ali Shaik, Ahmad

AU - Tan, Jonathan

AU - Lü, Junxuan

AU - Xing, Chengguo

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