Effect of caudal block on the plasma adrenaline and noradrenaline concentrations in paediatric patients undergoing ilioinguinal herniorrhaphy

Luis A. Gaitini, Mostafa Somri, Sonia Vaida, Milo Fradis, Edmond Sabo, Jorge Mogilner, Nurit Levy, Avital Greenberg, Sofia Lischinsky, Oren Zinder

Research output: Contribution to journalArticle

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Abstract

This study compared the effect of two anaesthetic techniques on the catecholamine levels in children undergoing ilioinguinal herniorrhaphy. Forty male paediatric patients ASA class I were allocated randomly to one of two groups: the control group (n = 20) received general anaesthesia including intravenous fentanyl; and the caudal group (n = 20) received caudal anaesthesia with bupivacaine 0.25% 1 mL kg-1 combined with general anaesthesia but without opioids. Plasma adrenaline and noradrenaline concentrations were measured at induction, at the end of surgery and in the post-anaesthesia care unit (PACU). In the caudal group, there were significant decreases in the adrenaline and noradrenaline concentrations at the end of surgery and in the PACU compared with baseline concentrations. In the control group, there was a significant increase in PACU concentrations of adrenaline and noradrenaline compared with baseline concentrations. These findings suggest that the addition of a caudal block to general anaesthesia in children undergoing ilioinguinal herniorrhaphy decreases significantly the neurohormonal responses to surgery.

Original languageEnglish (US)
Pages (from-to)92-97
Number of pages6
JournalEuropean Journal of Anaesthesiology
Volume16
Issue number2
DOIs
StatePublished - Mar 22 1999

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Herniorrhaphy
General Anesthesia
Epinephrine
Norepinephrine
Anesthesia
Pediatrics
Caudal Anesthesia
Control Groups
Bupivacaine
Fentanyl
Opioid Analgesics
Catecholamines
Anesthetics

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

Cite this

Gaitini, Luis A. ; Somri, Mostafa ; Vaida, Sonia ; Fradis, Milo ; Sabo, Edmond ; Mogilner, Jorge ; Levy, Nurit ; Greenberg, Avital ; Lischinsky, Sofia ; Zinder, Oren. / Effect of caudal block on the plasma adrenaline and noradrenaline concentrations in paediatric patients undergoing ilioinguinal herniorrhaphy. In: European Journal of Anaesthesiology. 1999 ; Vol. 16, No. 2. pp. 92-97.
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Effect of caudal block on the plasma adrenaline and noradrenaline concentrations in paediatric patients undergoing ilioinguinal herniorrhaphy. / Gaitini, Luis A.; Somri, Mostafa; Vaida, Sonia; Fradis, Milo; Sabo, Edmond; Mogilner, Jorge; Levy, Nurit; Greenberg, Avital; Lischinsky, Sofia; Zinder, Oren.

In: European Journal of Anaesthesiology, Vol. 16, No. 2, 22.03.1999, p. 92-97.

Research output: Contribution to journalArticle

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AU - Sabo, Edmond

AU - Mogilner, Jorge

AU - Levy, Nurit

AU - Greenberg, Avital

AU - Lischinsky, Sofia

AU - Zinder, Oren

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N2 - This study compared the effect of two anaesthetic techniques on the catecholamine levels in children undergoing ilioinguinal herniorrhaphy. Forty male paediatric patients ASA class I were allocated randomly to one of two groups: the control group (n = 20) received general anaesthesia including intravenous fentanyl; and the caudal group (n = 20) received caudal anaesthesia with bupivacaine 0.25% 1 mL kg-1 combined with general anaesthesia but without opioids. Plasma adrenaline and noradrenaline concentrations were measured at induction, at the end of surgery and in the post-anaesthesia care unit (PACU). In the caudal group, there were significant decreases in the adrenaline and noradrenaline concentrations at the end of surgery and in the PACU compared with baseline concentrations. In the control group, there was a significant increase in PACU concentrations of adrenaline and noradrenaline compared with baseline concentrations. These findings suggest that the addition of a caudal block to general anaesthesia in children undergoing ilioinguinal herniorrhaphy decreases significantly the neurohormonal responses to surgery.

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