Effect of coronary thrombus aspiration during primary percutaneous coronary intervention on one-year survival (from the fast-mi 2010 registry)

Etienne Puymirat, Nadia Aissaoui, Yves Cottin, Gérald Vanzetto, Didier Carrié, Karl Isaaz, Yann Valy, Didier Tchetche, François Schiele, Philippe Gabriel Steg, Tabassome Simon, Nicolas Danchin

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Abstract

Results from randomized trials evaluating thrombus aspiration (TA) in patients with ST-elevation myocardial infarction (STEMI) are conflicting. We assessed 1-year survival in STEMI patients participating in the French Registry of Acute ST-Elevation and non-ST-Elevation Myocardial Infarction (FAST-MI) 2010 according to the use of TA during primary percutaneous coronary intervention (PCI). FAST-MI 2010 is a nationwide French registry that included 4,169 patients with acute myocardial infarction at the end of 2010 in 213 centers. Of those, 2,087 patients had STEMI, of whom 1,538 had primary PCI, with TA used in 671 (44%). Patients with TA were younger (61 ± 13.5 vs 63 ± 14 years), with a similar risk score of the Global Registry of Acute Coronary Events (140 ± 31 vs 143 ± 34) and a shorter median time from symptom onset (245 vs 285 minutes); location of acute myocardial infarction, history of myocardial infarction, PCI, or coronary artery bypass surgery did not differ significantly. Thirty-day mortality was 2.1% versus 2.1% (adjusted p = 0.18), and the rate of 1-year survival was 95.5% versus 94.8%. Using fully adjusted Cox multivariate analysis, hazard ratio for 1-year death was 1.13 (95% confidence interval 0.66 to 1.94). After propensity score matching (480 patients per group), 1-year survival was also similar with both strategies. In a real-world setting of patients admitted with STEMI, the use of TA during primary PCI was not associated with improved 1-year survival.

Original languageEnglish (US)
Pages (from-to)1651-1657
Number of pages7
JournalAmerican Journal of Cardiology
Volume114
Issue number11
DOIs
StatePublished - Dec 1 2014

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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    Puymirat, E., Aissaoui, N., Cottin, Y., Vanzetto, G., Carrié, D., Isaaz, K., Valy, Y., Tchetche, D., Schiele, F., Steg, P. G., Simon, T., & Danchin, N. (2014). Effect of coronary thrombus aspiration during primary percutaneous coronary intervention on one-year survival (from the fast-mi 2010 registry). American Journal of Cardiology, 114(11), 1651-1657. https://doi.org/10.1016/j.amjcard.2014.08.039