Effect of exercise intensity on plasma prostaglandin concentrations in horses.

L. A. Mitten, K. W. Hinchcliff, Joy Lee Pate, C. W. Kohn, K. H. McKeever

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Exertion has an effect on plasma, serum, and/or urine prostanoid concentrations in many species. We investigated the effect of exercise intensity on plasma prostaglandin concentrations during and after exercise in horses. Six Thoroughbreds completed 4 trials: 3 exercise trials (low-, medium-, and high-speed) and 1 nonexercise (control) trial on a high-speed treadmill. Blood samples were collected from a jugular catheter before, during, and after exercise. The PCV and blood lactate, plasma protein, plasma prostacyclin (6-keto-PGF1 alpha), thromboxane B2 (TXB2), and prostaglandin E2 (PGE2) concentrations were measured before, during, and after exercise. Exercise significantly (P = 0.001) increased plasma TXB2 concentration during and after exercise in the low-, medium-, and high-speed trials, although effect of exercise intensity was not detected. Exercise was associated with an increase in PCV and blood lactate and plasma protein concentrations. There was no effect of exercise on plasma 6-keto-PGF1 alpha concentrations; PGE2 was not detected in plasma from any horse in any trial.

Original languageEnglish (US)
Pages (from-to)122-126
Number of pages5
JournalAmerican Journal of Veterinary Research
Volume56
Issue number1
StatePublished - Jan 1995

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prostaglandins
Horses
Prostaglandins
exercise
horses
6-Ketoprostaglandin F1 alpha
Blood Proteins
Thromboxane B2
Dinoprostone
thromboxanes
Lactic Acid
blood proteins
lactates
blood
prostacyclin
Epoprostenol
exercise equipment
blood serum
Neck
Catheters

All Science Journal Classification (ASJC) codes

  • veterinary(all)

Cite this

Mitten, L. A., Hinchcliff, K. W., Pate, J. L., Kohn, C. W., & McKeever, K. H. (1995). Effect of exercise intensity on plasma prostaglandin concentrations in horses. American Journal of Veterinary Research, 56(1), 122-126.
Mitten, L. A. ; Hinchcliff, K. W. ; Pate, Joy Lee ; Kohn, C. W. ; McKeever, K. H. / Effect of exercise intensity on plasma prostaglandin concentrations in horses. In: American Journal of Veterinary Research. 1995 ; Vol. 56, No. 1. pp. 122-126.
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Mitten, LA, Hinchcliff, KW, Pate, JL, Kohn, CW & McKeever, KH 1995, 'Effect of exercise intensity on plasma prostaglandin concentrations in horses.', American Journal of Veterinary Research, vol. 56, no. 1, pp. 122-126.

Effect of exercise intensity on plasma prostaglandin concentrations in horses. / Mitten, L. A.; Hinchcliff, K. W.; Pate, Joy Lee; Kohn, C. W.; McKeever, K. H.

In: American Journal of Veterinary Research, Vol. 56, No. 1, 01.1995, p. 122-126.

Research output: Contribution to journalArticle

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