Effect of Exogenous Bovine Somatotropin on Mammary Lipid Metabolism and Milk Yield in Lactating Dairy Cows

D. S. Lough, L. D. Muller, R. S. Kensinger, Lester C. Griel, Jr., Carl Daniel Azzara

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Eight lactating Holstein cows were used to study the effect of bovine somatotropin on mammary lipid metabolism, milk production, and milk composition. Eight cows were injected with either ex-cipient (n = 4) or 50 IU somatotropin/d (n = 4). A 2-wk adjustment period preceded a 10-d period when treatments were administered. On d 9, serial blood samples were collected from 2 to 5 h post-injection to determine concentrations of somatotropin and metabolites in plasma. Mammary tissue biopsies were obtained 2 to 3 h after a.m. milking on d 10 to determine lipoprotein lipase activity and in vitro rates of acetate incorporation into fatty acids and acetate oxidation by mammary tissue slices. Activity of lipoprotein lipase in milk and mammary tissue and rate of acetate metabolism by mammary tissue were not affected by treatment. The following means for placebo and somatotropin, respectively, were: milk production (21.5 and 24.8 kg/d), milk fat (3.8 and 4.0%), and 4% FCM (20.7 and 25.1 kg/d). Plasma concentrations of somatotropin (3.0 and 43.4 ng/ml) and free fatty acids (105.6 and 219.5 μeq/L) were significantly elevated with somatotropin. The injection of somatotropin into lactating dairy cows did not affect the mechanisms of fatty acid synthesis or metabolism evaluated in this study.

Original languageEnglish (US)
Pages (from-to)1469-1476
Number of pages8
JournalJournal of dairy science
Volume72
Issue number6
DOIs
StatePublished - Jan 1 1989

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Lipid Metabolism
lipid metabolism
somatotropin
Growth Hormone
breasts
milk yield
Milk
Breast
dairy cows
Acetates
Lipoprotein Lipase
lipoprotein lipase
acetates
Fatty Acids
milk production
Injections
injection
fatty acids
cows
metabolism

All Science Journal Classification (ASJC) codes

  • Food Science
  • Animal Science and Zoology
  • Genetics

Cite this

Lough, D. S. ; Muller, L. D. ; Kensinger, R. S. ; Griel, Jr., Lester C. ; Azzara, Carl Daniel. / Effect of Exogenous Bovine Somatotropin on Mammary Lipid Metabolism and Milk Yield in Lactating Dairy Cows. In: Journal of dairy science. 1989 ; Vol. 72, No. 6. pp. 1469-1476.
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Effect of Exogenous Bovine Somatotropin on Mammary Lipid Metabolism and Milk Yield in Lactating Dairy Cows. / Lough, D. S.; Muller, L. D.; Kensinger, R. S.; Griel, Jr., Lester C.; Azzara, Carl Daniel.

In: Journal of dairy science, Vol. 72, No. 6, 01.01.1989, p. 1469-1476.

Research output: Contribution to journalArticle

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