Effect of HIV infection on hepatitis C

M. Elaine Eyster, M. S. Hershey

    Research output: Contribution to journalShort survey

    2 Citations (Scopus)

    Abstract

    Hepatitis C (HCV) is a common infection that can lead to chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Although the rates of clinical progression are highly variable, chronic HCV infection leads to cirrhosis in at least 20% of patients within two decades of the onset of infection (1). For those who are coinfected with the human immunodeficiency virus (HIV), progression to end-stage liver disease is more rapid (2-9). Coinfection with HIV may also increase the rates of perinatal and sexual transmission of HCV (10-13). This review will focus on the effect of HIV on the natural history and transmission of chronic HCV infections. The possible effects of HIV and its associated immune deficiency state on HCV viral load and genetic heterogeneity will be discussed.

    Original languageEnglish (US)
    Pages (from-to)189-206
    Number of pages18
    JournalViral Hepatitis Reviews
    Volume4
    Issue number3
    StatePublished - Jan 1 1998

    Fingerprint

    Virus Diseases
    Hepatitis C
    HIV
    Infection
    Fibrosis
    End Stage Liver Disease
    Genetic Heterogeneity
    Chronic Hepatitis
    Natural History
    Viral Load
    Coinfection
    Hepatocellular Carcinoma

    All Science Journal Classification (ASJC) codes

    • Hepatology
    • Virology

    Cite this

    Eyster, M. Elaine ; Hershey, M. S. / Effect of HIV infection on hepatitis C. In: Viral Hepatitis Reviews. 1998 ; Vol. 4, No. 3. pp. 189-206.
    @article{7988070e523644378191bf61fc8fe871,
    title = "Effect of HIV infection on hepatitis C",
    abstract = "Hepatitis C (HCV) is a common infection that can lead to chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Although the rates of clinical progression are highly variable, chronic HCV infection leads to cirrhosis in at least 20{\%} of patients within two decades of the onset of infection (1). For those who are coinfected with the human immunodeficiency virus (HIV), progression to end-stage liver disease is more rapid (2-9). Coinfection with HIV may also increase the rates of perinatal and sexual transmission of HCV (10-13). This review will focus on the effect of HIV on the natural history and transmission of chronic HCV infections. The possible effects of HIV and its associated immune deficiency state on HCV viral load and genetic heterogeneity will be discussed.",
    author = "Eyster, {M. Elaine} and Hershey, {M. S.}",
    year = "1998",
    month = "1",
    day = "1",
    language = "English (US)",
    volume = "4",
    pages = "189--206",
    journal = "Viral Hepatitis Reviews",
    issn = "1081-7050",
    publisher = "W.B. Saunders Ltd",
    number = "3",

    }

    Eyster, ME & Hershey, MS 1998, 'Effect of HIV infection on hepatitis C', Viral Hepatitis Reviews, vol. 4, no. 3, pp. 189-206.

    Effect of HIV infection on hepatitis C. / Eyster, M. Elaine; Hershey, M. S.

    In: Viral Hepatitis Reviews, Vol. 4, No. 3, 01.01.1998, p. 189-206.

    Research output: Contribution to journalShort survey

    TY - JOUR

    T1 - Effect of HIV infection on hepatitis C

    AU - Eyster, M. Elaine

    AU - Hershey, M. S.

    PY - 1998/1/1

    Y1 - 1998/1/1

    N2 - Hepatitis C (HCV) is a common infection that can lead to chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Although the rates of clinical progression are highly variable, chronic HCV infection leads to cirrhosis in at least 20% of patients within two decades of the onset of infection (1). For those who are coinfected with the human immunodeficiency virus (HIV), progression to end-stage liver disease is more rapid (2-9). Coinfection with HIV may also increase the rates of perinatal and sexual transmission of HCV (10-13). This review will focus on the effect of HIV on the natural history and transmission of chronic HCV infections. The possible effects of HIV and its associated immune deficiency state on HCV viral load and genetic heterogeneity will be discussed.

    AB - Hepatitis C (HCV) is a common infection that can lead to chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Although the rates of clinical progression are highly variable, chronic HCV infection leads to cirrhosis in at least 20% of patients within two decades of the onset of infection (1). For those who are coinfected with the human immunodeficiency virus (HIV), progression to end-stage liver disease is more rapid (2-9). Coinfection with HIV may also increase the rates of perinatal and sexual transmission of HCV (10-13). This review will focus on the effect of HIV on the natural history and transmission of chronic HCV infections. The possible effects of HIV and its associated immune deficiency state on HCV viral load and genetic heterogeneity will be discussed.

    UR - http://www.scopus.com/inward/record.url?scp=0031687144&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0031687144&partnerID=8YFLogxK

    M3 - Short survey

    AN - SCOPUS:0031687144

    VL - 4

    SP - 189

    EP - 206

    JO - Viral Hepatitis Reviews

    JF - Viral Hepatitis Reviews

    SN - 1081-7050

    IS - 3

    ER -