The behavior of 21-day old rats whose mothers were administered heroin (5 mg/kg daily) throughout gestation and lactation was studied utilizing an activity wheel, activity cage, open field test, and step-down latency times from an elevated platform. The total score of all behavioral tasks of offspring from heroin-injected females was statistically different from that of pups from saline-injected mothers, with heroin-treated animals appearing more active.
All Science Journal Classification (ASJC) codes
- Clinical Biochemistry
- Biological Psychiatry
- Behavioral Neuroscience