Effect of maternally administered heroin on the motor activity of rat offspring

Research output: Contribution to journalArticle

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Abstract

The behavior of 21-day old rats whose mothers were administered heroin (5 mg/kg daily) throughout gestation and lactation was studied utilizing an activity wheel, activity cage, open field test, and step-down latency times from an elevated platform. The total score of all behavioral tasks of offspring from heroin-injected females was statistically different from that of pups from saline-injected mothers, with heroin-treated animals appearing more active.

Original languageEnglish (US)
Pages (from-to)281-284
Number of pages4
JournalPharmacology, Biochemistry and Behavior
Volume7
Issue number3
DOIs
StatePublished - Sep 1977

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Toxicology
  • Pharmacology
  • Clinical Biochemistry
  • Biological Psychiatry
  • Behavioral Neuroscience

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