Effects of a DASH-like diet containing lean beef on vascular health

M. A. Roussell, A. M. Hill, T. L. Gaugler, S. G. West, J. S. Ulbrecht, J. P. Vanden Heuvel, P. J. Gillies, P. M. Kris-Etherton

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A DASH (dietary approaches to stop hypertension) dietary pattern rich in fruits and vegetables and low-fat dairy products with increased dietary protein provided primarily from plant protein sources decreases blood pressure. No studies, however, have evaluated the effects of a DASH-like diet with increased dietary protein from lean beef on blood pressure and vascular health. The aim of this study was to study the effect of DASH-like diets that provided different amounts of protein from lean beef (DASH 28 g beef per day; beef in an optimal lean diet (BOLD) 113 g beef per day; beef in an optimal lean diet plus additional protein (BOLD+) 153 g beef per day) on blood pressure, endothelial function and vascular reactivity versus a healthy American diet (HAD). Using a randomized, crossover study design, 36 normotensive participants (systolic blood pressure (SBP), 116±3.6 mm Hg) were fed four isocaloric diets,: HAD (33% total fat, 12% saturated fatty acids (SFA), 17% protein (PRO), 20 g beef per day), DASH (27% total fat, 6% SFA, 18% PRO, 28 g beef per day), BOLD (28% total fat, 6% SFA, 19% PRO, 113 g beef per day) and BOLD+ (28% total fat, 6% SFA, 27% PRO, 153 g beef per day), for 5 weeks. SBP decreased (P<0.05) in subjects on the BOLD+ diet (111.4±1.9 mm Hg) versus HAD (115.7±1.9). There were no significant effects of the DASH and BOLD diets on SBP. Augmentation index (AI) was significantly reduced in participants on the BOLD diet (-4.1%). There were no significant effects of the dietary treatments on diastolic blood pressure or endothelial function (as measured by peripheral arterial tonometry). A moderate protein DASH-like diet including lean beef decreased SBP in normotensive individuals. The inclusion of lean beef in a heart healthy diet also reduced peripheral vascular constriction.

Original languageEnglish (US)
Pages (from-to)600-605
Number of pages6
JournalJournal of Human Hypertension
Volume28
Issue number10
DOIs
StatePublished - Jan 1 2014

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Blood Vessels
Diet
Hypertension
Health
Blood Pressure
Fats
Dietary Proteins
Fatty Acids
Red Meat
Proteins
Cross-Over Studies
Plant Proteins
Dairy Products
Manometry
Constriction
Vegetables
Fruit

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Roussell, M. A. ; Hill, A. M. ; Gaugler, T. L. ; West, S. G. ; Ulbrecht, J. S. ; Vanden Heuvel, J. P. ; Gillies, P. J. ; Kris-Etherton, P. M. / Effects of a DASH-like diet containing lean beef on vascular health. In: Journal of Human Hypertension. 2014 ; Vol. 28, No. 10. pp. 600-605.
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abstract = "A DASH (dietary approaches to stop hypertension) dietary pattern rich in fruits and vegetables and low-fat dairy products with increased dietary protein provided primarily from plant protein sources decreases blood pressure. No studies, however, have evaluated the effects of a DASH-like diet with increased dietary protein from lean beef on blood pressure and vascular health. The aim of this study was to study the effect of DASH-like diets that provided different amounts of protein from lean beef (DASH 28 g beef per day; beef in an optimal lean diet (BOLD) 113 g beef per day; beef in an optimal lean diet plus additional protein (BOLD+) 153 g beef per day) on blood pressure, endothelial function and vascular reactivity versus a healthy American diet (HAD). Using a randomized, crossover study design, 36 normotensive participants (systolic blood pressure (SBP), 116±3.6 mm Hg) were fed four isocaloric diets,: HAD (33{\%} total fat, 12{\%} saturated fatty acids (SFA), 17{\%} protein (PRO), 20 g beef per day), DASH (27{\%} total fat, 6{\%} SFA, 18{\%} PRO, 28 g beef per day), BOLD (28{\%} total fat, 6{\%} SFA, 19{\%} PRO, 113 g beef per day) and BOLD+ (28{\%} total fat, 6{\%} SFA, 27{\%} PRO, 153 g beef per day), for 5 weeks. SBP decreased (P<0.05) in subjects on the BOLD+ diet (111.4±1.9 mm Hg) versus HAD (115.7±1.9). There were no significant effects of the DASH and BOLD diets on SBP. Augmentation index (AI) was significantly reduced in participants on the BOLD diet (-4.1{\%}). There were no significant effects of the dietary treatments on diastolic blood pressure or endothelial function (as measured by peripheral arterial tonometry). A moderate protein DASH-like diet including lean beef decreased SBP in normotensive individuals. The inclusion of lean beef in a heart healthy diet also reduced peripheral vascular constriction.",
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Effects of a DASH-like diet containing lean beef on vascular health. / Roussell, M. A.; Hill, A. M.; Gaugler, T. L.; West, S. G.; Ulbrecht, J. S.; Vanden Heuvel, J. P.; Gillies, P. J.; Kris-Etherton, P. M.

In: Journal of Human Hypertension, Vol. 28, No. 10, 01.01.2014, p. 600-605.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effects of a DASH-like diet containing lean beef on vascular health

AU - Roussell, M. A.

AU - Hill, A. M.

AU - Gaugler, T. L.

AU - West, S. G.

AU - Ulbrecht, J. S.

AU - Vanden Heuvel, J. P.

AU - Gillies, P. J.

AU - Kris-Etherton, P. M.

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