Effects of conjugated linoleic acid (CLA) on immune responses, body composition and stearoyl-CoA desaturase

James M. Ntambi, Youngjin Choi, Yeonhwa Park, Jeffrey M. Peters, Michael W. Pariza

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Conjugated linoleic acid (CLA) has shown a wide range of biologically beneficial effects; reduction of incidence and severity of animal carcinogenesis, reduction of the adverse effects of immune stimulation, reduction of severity of atherosclerosis, growth promotion in young rats, and modulation of stearoyl-CoA desaturase (SCD). One of the most interesting aspects of CLA is its ability to reduce body fat while enhancing lean body mass which is associated with the trans-10,cis-72 isomer of CLA. The effects of CLA are unique characteristics that have not been observed with other polyunsaturated fatty acids. In this review, we will focus on the effects of CLA on immune responses, body compositional changes and stearoyl-CoA desaturase.

Original languageEnglish (US)
Pages (from-to)617-627
Number of pages11
JournalCanadian Journal of Applied Physiology
Volume27
Issue number6
DOIs
StatePublished - Dec 2002

All Science Journal Classification (ASJC) codes

  • Physiology
  • Orthopedics and Sports Medicine

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