TY - JOUR
T1 - Effects of dietary Capsicum oleoresin on productivity and immune responses in lactating dairy cows
AU - Oh, J.
AU - Giallongo, F.
AU - Frederick, T.
AU - Pate, J.
AU - Walusimbi, S.
AU - Elias, R. J.
AU - Wall, E. H.
AU - Bravo, D.
AU - Hristov, A. N.
N1 - Funding Information:
The authors thank Pancosma S.A. (Geneva, Switzerland) for providing partial financial support for this project and the CAP used in the experiment, Pennsylvania State University’s Animal Diagnostic Laboratory and Dona Wijetunge for providing S. ubris , Ling Tao and Yufan Zhang in the Department of Food Science (Pennsylvania State University) for analysis of oxidative stress markers, and the staff of the Department of Animal Science Dairy Center (Pennsylvania State University) for their conscientious care of the experimental cows.
Publisher Copyright:
© 2015 American Dairy Science Association.
PY - 2015/9/1
Y1 - 2015/9/1
N2 - This study investigated the effect of Capsicum oleoresin in granular form (CAP) on nutrient digestibility, immune responses, oxidative stress markers, blood chemistry, rumen fermentation, rumen bacterial populations, and productivity of lactating dairy cows. Eight multiparous Holstein cows, including 3 ruminally cannulated, were used in a replicated 4. ×. 4 Latin square design experiment. Experimental periods were 25 d in duration, including a 14-d adaptation and an 11-d data collection and sampling period. Treatments included control (no CAP) and daily supplementation of 250, 500, or 1,000 mg of CAP/cow. Dry matter intake was not affected by CAP (average 27.0. ±. 0.64 kg/d), but milk yield tended to quadratically increase with CAP supplementation (50.3 to 51.9. ±. 0.86 kg/d). Capsicum oleoresin quadratically increased energy-corrected milk yield, but had no effect on milk fat concentration. Rumen fermentation variables, apparent total-tract digestibility of nutrients, and N excretion in feces and urine were not affected by CAP. Blood serum β-hydroxybutyrate was quadratically increased by CAP, whereas the concentration of nonesterified fatty acids was similar among treatments. Rumen populations of Bacteroidales, Prevotella, and Roseburia decreased and Butyrivibrio increased quadratically with CAP supplementation. T cell phenotypes were not affected by treatment. Mean fluorescence intensity for phagocytic activity of neutrophils tended to be quadratically increased by CAP. Numbers of neutrophils and eosinophils and the ratio of neutrophils to lymphocytes in peripheral blood linearly increased with increasing CAP. Oxidative stress markers were not affected by CAP. Overall, in the conditions of this experiment, CAP did not affect feed intake, rumen fermentation, nutrient digestibility, T cell phenotypes, and oxidative stress markers. However, energy-corrected milk yield was quadratically increased by CAP, possibly as a result of enhanced mobilization of body fat reserves. In addition, CAP increased neutrophil activity and immune cells related to acute phase immune response.
AB - This study investigated the effect of Capsicum oleoresin in granular form (CAP) on nutrient digestibility, immune responses, oxidative stress markers, blood chemistry, rumen fermentation, rumen bacterial populations, and productivity of lactating dairy cows. Eight multiparous Holstein cows, including 3 ruminally cannulated, were used in a replicated 4. ×. 4 Latin square design experiment. Experimental periods were 25 d in duration, including a 14-d adaptation and an 11-d data collection and sampling period. Treatments included control (no CAP) and daily supplementation of 250, 500, or 1,000 mg of CAP/cow. Dry matter intake was not affected by CAP (average 27.0. ±. 0.64 kg/d), but milk yield tended to quadratically increase with CAP supplementation (50.3 to 51.9. ±. 0.86 kg/d). Capsicum oleoresin quadratically increased energy-corrected milk yield, but had no effect on milk fat concentration. Rumen fermentation variables, apparent total-tract digestibility of nutrients, and N excretion in feces and urine were not affected by CAP. Blood serum β-hydroxybutyrate was quadratically increased by CAP, whereas the concentration of nonesterified fatty acids was similar among treatments. Rumen populations of Bacteroidales, Prevotella, and Roseburia decreased and Butyrivibrio increased quadratically with CAP supplementation. T cell phenotypes were not affected by treatment. Mean fluorescence intensity for phagocytic activity of neutrophils tended to be quadratically increased by CAP. Numbers of neutrophils and eosinophils and the ratio of neutrophils to lymphocytes in peripheral blood linearly increased with increasing CAP. Oxidative stress markers were not affected by CAP. Overall, in the conditions of this experiment, CAP did not affect feed intake, rumen fermentation, nutrient digestibility, T cell phenotypes, and oxidative stress markers. However, energy-corrected milk yield was quadratically increased by CAP, possibly as a result of enhanced mobilization of body fat reserves. In addition, CAP increased neutrophil activity and immune cells related to acute phase immune response.
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U2 - 10.3168/jds.2014-9294
DO - 10.3168/jds.2014-9294
M3 - Article
C2 - 26188565
AN - SCOPUS:84939157257
SN - 0022-0302
VL - 98
SP - 6327
EP - 6339
JO - Journal of Dairy Science
JF - Journal of Dairy Science
IS - 9
ER -