Effects of lesions in the basolateral amygdala on fluid intake in the rat

Barbara J. Rolls, Edmund T. Rolls

Research output: Contribution to journalArticle

76 Citations (Scopus)

Abstract

Conducted 6 experiments with 33 rats with bilateral lesions in the lateral amygdaloid region and 22 intact controls. Drinking response to hypertonic saline, a cellular thirst stimulus, and to isoproterenol, probably an extracellular thirst stimulus, was normal in lesioned Ss. The overnight water intake of the lesioned Ss was a little higher than normal. However, the lesioned Ss showed a major impairment in learning to avoid ingesting a poisonous solution of LiCl when they were thirsty and an increased preference of 25% sucrose in a 2-bottle sucrose-water test. It is concluded that the basolateral region of the amygdala is involved in the effects of previous experience on drinking and not primarily in the cellular or extracellular controls of drinking. (25 ref.) (PsycINFO Database Record (c) 2006 APA, all rights reserved).

Original languageEnglish (US)
Pages (from-to)240-247
Number of pages8
JournalJournal of Comparative and Physiological Psychology
Volume83
Issue number2
DOIs
StatePublished - May 1 1973

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Drinking
Thirst
Sucrose
Isoproterenol
Learning
Basolateral Nuclear Complex
Water

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

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Effects of lesions in the basolateral amygdala on fluid intake in the rat. / Rolls, Barbara J.; Rolls, Edmund T.

In: Journal of Comparative and Physiological Psychology, Vol. 83, No. 2, 01.05.1973, p. 240-247.

Research output: Contribution to journalArticle

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