Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy: A pilot randomized double-blind study

Gwinnett Ladson, William Dodson, Stephanie D. Sweet, Anthony E. Archibong, Allen Kunselman, Laurence Demers, Peter Lee, Nancy Williams, Ponjola Coney, Richard Legro

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Our small study does not support the addition of metformin to the lifestyle of adolescents. Although there are favorable trends toward hyperandrogenism with metformin, these must be balanced against the increased rate of gastrointestinal side effects. However, other treatments were associated with an improved quality of life.

Original languageEnglish (US)
JournalFertility and sterility
Volume95
Issue number8
DOIs
StatePublished - Jun 30 2011

Fingerprint

Polycystic Ovary Syndrome
Metformin
Double-Blind Method
Life Style
Hyperandrogenism
Quality of Life
Therapeutics

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology

Cite this

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Effects of metformin in adolescents with polycystic ovary syndrome undertaking lifestyle therapy : A pilot randomized double-blind study. / Ladson, Gwinnett; Dodson, William; Sweet, Stephanie D.; Archibong, Anthony E.; Kunselman, Allen; Demers, Laurence; Lee, Peter; Williams, Nancy; Coney, Ponjola; Legro, Richard.

In: Fertility and sterility, Vol. 95, No. 8, 30.06.2011.

Research output: Contribution to journalArticle

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AU - Ladson, Gwinnett

AU - Dodson, William

AU - Sweet, Stephanie D.

AU - Archibong, Anthony E.

AU - Kunselman, Allen

AU - Demers, Laurence

AU - Lee, Peter

AU - Williams, Nancy

AU - Coney, Ponjola

AU - Legro, Richard

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