Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Plants produce an extensive array of organic compounds derived from secondary metabolism that may be useful in animal nutrition because of their chemical makeup. These plant-derived bio-active compounds (PBAC), also referred to as phytonutrients or phytobiotics, have been shown to express antimicrobial activities against a wide range of bacteria, yeast, and fungi and have been investigated as alternatives to rumen modifiers, such as ionophoric antibiotics, in animal nutrition. PBAC have also been studied as inhibitors of pathogens that impact animal health and productivity, modulate the immune system, and reduce stress. A large number of in vitro, in situ, and in vivo studies on the effects of PBAC on ruminal fermentation have been published in recent years. Some reports have concluded that PBAC may inhibit deamination of amino acids and methanogenesis and shift fermentation towards propionate and butyrate. Responses, however, have been highly variable. Overall, hydrolysable and condensed tannins may offer an opportunity to reduce rumen methane production, although intake and animal productivity may be compromised. Most of the experiments with PBAC have been conducted in vitro. Although in vitro data are useful for screening purposes, the true value of PBAC for altering rumen microbial fermentation and ultimately enhancing animal production must be assessed in vivo and in long-term trials. Another, relatively new area of research is the effects of PBAC on immunity and animal health. PBAC such as garlic, curcumin, and capsicum have modulatory effects on the adaptive immune system in monogastric species and similar properties may be expected in ruminants. Studies with dairy cows have indicated that some PBAC delivered postruminally increase neutrophil activity and the numbers of immune cells related to acute phase immune response. Overall, some PBAC may be beneficial as rumen modifiers and may positively affect animal immunity, health, and productivity, but more and long-term studies are needed to fully elucidate these effects in ruminant animals.

Original languageEnglish (US)
Title of host publicationMedicinal and Aromatic Crops
Subtitle of host publicationProduction, Phytochemistry, and Utilization
EditorsValtcho D. Jeliazkov (Zheljazkov), Charles L. Cantrell
PublisherAmerican Chemical Society
Pages167-186
Number of pages20
ISBN (Electronic)9780841231276
DOIs
StatePublished - Jan 1 2016

Publication series

NameACS Symposium Series
Volume1218
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

Fingerprint

Fermentation
Nutrients
Animals
Productivity
Immune system
Health
Nutrition
Hydrolyzable Tannins
Proanthocyanidins
Curcumin
Dairies
Butyrates
Methane
Propionates
Phytochemicals
Pathogens
Antibiotics
Fungi
Organic compounds
Yeast

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Oh, J., & Hristov, A. N. (2016). Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals. In V. D. Jeliazkov (Zheljazkov), & C. L. Cantrell (Eds.), Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization (pp. 167-186). (ACS Symposium Series; Vol. 1218). American Chemical Society. https://doi.org/10.1021/bk-2016-1218.ch011
Oh, J. ; Hristov, Alexander Nikolov. / Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals. Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization. editor / Valtcho D. Jeliazkov (Zheljazkov) ; Charles L. Cantrell. American Chemical Society, 2016. pp. 167-186 (ACS Symposium Series).
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Oh, J & Hristov, AN 2016, Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals. in VD Jeliazkov (Zheljazkov) & CL Cantrell (eds), Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization. ACS Symposium Series, vol. 1218, American Chemical Society, pp. 167-186. https://doi.org/10.1021/bk-2016-1218.ch011

Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals. / Oh, J.; Hristov, Alexander Nikolov.

Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization. ed. / Valtcho D. Jeliazkov (Zheljazkov); Charles L. Cantrell. American Chemical Society, 2016. p. 167-186 (ACS Symposium Series; Vol. 1218).

Research output: Chapter in Book/Report/Conference proceedingChapter

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N2 - Plants produce an extensive array of organic compounds derived from secondary metabolism that may be useful in animal nutrition because of their chemical makeup. These plant-derived bio-active compounds (PBAC), also referred to as phytonutrients or phytobiotics, have been shown to express antimicrobial activities against a wide range of bacteria, yeast, and fungi and have been investigated as alternatives to rumen modifiers, such as ionophoric antibiotics, in animal nutrition. PBAC have also been studied as inhibitors of pathogens that impact animal health and productivity, modulate the immune system, and reduce stress. A large number of in vitro, in situ, and in vivo studies on the effects of PBAC on ruminal fermentation have been published in recent years. Some reports have concluded that PBAC may inhibit deamination of amino acids and methanogenesis and shift fermentation towards propionate and butyrate. Responses, however, have been highly variable. Overall, hydrolysable and condensed tannins may offer an opportunity to reduce rumen methane production, although intake and animal productivity may be compromised. Most of the experiments with PBAC have been conducted in vitro. Although in vitro data are useful for screening purposes, the true value of PBAC for altering rumen microbial fermentation and ultimately enhancing animal production must be assessed in vivo and in long-term trials. Another, relatively new area of research is the effects of PBAC on immunity and animal health. PBAC such as garlic, curcumin, and capsicum have modulatory effects on the adaptive immune system in monogastric species and similar properties may be expected in ruminants. Studies with dairy cows have indicated that some PBAC delivered postruminally increase neutrophil activity and the numbers of immune cells related to acute phase immune response. Overall, some PBAC may be beneficial as rumen modifiers and may positively affect animal immunity, health, and productivity, but more and long-term studies are needed to fully elucidate these effects in ruminant animals.

AB - Plants produce an extensive array of organic compounds derived from secondary metabolism that may be useful in animal nutrition because of their chemical makeup. These plant-derived bio-active compounds (PBAC), also referred to as phytonutrients or phytobiotics, have been shown to express antimicrobial activities against a wide range of bacteria, yeast, and fungi and have been investigated as alternatives to rumen modifiers, such as ionophoric antibiotics, in animal nutrition. PBAC have also been studied as inhibitors of pathogens that impact animal health and productivity, modulate the immune system, and reduce stress. A large number of in vitro, in situ, and in vivo studies on the effects of PBAC on ruminal fermentation have been published in recent years. Some reports have concluded that PBAC may inhibit deamination of amino acids and methanogenesis and shift fermentation towards propionate and butyrate. Responses, however, have been highly variable. Overall, hydrolysable and condensed tannins may offer an opportunity to reduce rumen methane production, although intake and animal productivity may be compromised. Most of the experiments with PBAC have been conducted in vitro. Although in vitro data are useful for screening purposes, the true value of PBAC for altering rumen microbial fermentation and ultimately enhancing animal production must be assessed in vivo and in long-term trials. Another, relatively new area of research is the effects of PBAC on immunity and animal health. PBAC such as garlic, curcumin, and capsicum have modulatory effects on the adaptive immune system in monogastric species and similar properties may be expected in ruminants. Studies with dairy cows have indicated that some PBAC delivered postruminally increase neutrophil activity and the numbers of immune cells related to acute phase immune response. Overall, some PBAC may be beneficial as rumen modifiers and may positively affect animal immunity, health, and productivity, but more and long-term studies are needed to fully elucidate these effects in ruminant animals.

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Oh J, Hristov AN. Effects of plant-derived bio-active compounds on rumen fermentation, nutrient utilization, immune response, and productivity of ruminant animals. In Jeliazkov (Zheljazkov) VD, Cantrell CL, editors, Medicinal and Aromatic Crops: Production, Phytochemistry, and Utilization. American Chemical Society. 2016. p. 167-186. (ACS Symposium Series). https://doi.org/10.1021/bk-2016-1218.ch011