Effects of synaptic coupling on phase response curve of neurons

Meili Lu, Yanqiu Che, Huiyan Li, Xile Wei, Jiang Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The problem of phase response curves (PRCs) for two neuronal oscillators coupled with chemical synapse is considered in this paper. For small inputs, the PRCs can be computed for a linearized model for the system on the limit cycle. But for an input with large amplitude, the PRCs could be computed by direct method. The shape of phase response curve for single oscillator is depending on the influence of external stimuli, while in neuron networks, neurons are coupled to each other, and the couplings can affect the response of the neuronal oscillators to stimulation. Based on the direct PRCs, we investigate the effects of excitatory and inhibitory synaptic couplings on the PRCs of oscillators, and find that the effects of couplings on phase response of neurons are not only depending on the nature of couplings, but also on the initial phase errors between coupled neurons, which can be explained by the phase difference coupling function.

Original languageEnglish (US)
Title of host publicationProceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages745-749
Number of pages5
ISBN (Electronic)9781479958382
DOIs
StatePublished - Jan 1 2014
Event2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014 - Dalian, China
Duration: Oct 14 2014Oct 16 2014

Publication series

NameProceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014

Other

Other2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014
CountryChina
CityDalian
Period10/14/1410/16/14

Fingerprint

Neurons
Synapses

All Science Journal Classification (ASJC) codes

  • Signal Processing
  • Health Information Management
  • Information Systems
  • Biomedical Engineering
  • Health Informatics

Cite this

Lu, M., Che, Y., Li, H., Wei, X., & Wang, J. (2014). Effects of synaptic coupling on phase response curve of neurons. In Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014 (pp. 745-749). [7002872] (Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BMEI.2014.7002872
Lu, Meili ; Che, Yanqiu ; Li, Huiyan ; Wei, Xile ; Wang, Jiang. / Effects of synaptic coupling on phase response curve of neurons. Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 745-749 (Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014).
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Lu, M, Che, Y, Li, H, Wei, X & Wang, J 2014, Effects of synaptic coupling on phase response curve of neurons. in Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014., 7002872, Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014, Institute of Electrical and Electronics Engineers Inc., pp. 745-749, 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014, Dalian, China, 10/14/14. https://doi.org/10.1109/BMEI.2014.7002872

Effects of synaptic coupling on phase response curve of neurons. / Lu, Meili; Che, Yanqiu; Li, Huiyan; Wei, Xile; Wang, Jiang.

Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 745-749 7002872 (Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Lu M, Che Y, Li H, Wei X, Wang J. Effects of synaptic coupling on phase response curve of neurons. In Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014. Institute of Electrical and Electronics Engineers Inc. 2014. p. 745-749. 7002872. (Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014). https://doi.org/10.1109/BMEI.2014.7002872