Efficacy of Performing Red‐Cell Antibody Elutions in Patients with a Positive Direct Antiglobulin Test

Ronald Domen, Jean Grattan

Research output: Contribution to journalArticle

6 Scopus citations


Abstract. Red blood cell antibody elutions are often routinely performed whenever a positive direct antiglobulin test (DAT) is encountered. To evaluate the efficacy of performing routine red‐cell elutions we reviewed our antibody elution data. Of 122 eluates, 83 were negative, 35 were warm panagglutinins, 2 were felt to be transfusion‐induced alloantibodies, 1 was passively acquired anti‐A, and 1 was inconclusive. One of the eluted alloantibodies was not demonstrable in the serum. Thus, only 1 (0.8%) of the eluates provided important information not readily available through serum testing alone. We conclude that extensive serologic evaluation of a positive DAT should be reserved for those patients who have been recently transfused or are suspected of having immune hemolysis.

Original languageEnglish (US)
Pages (from-to)324-326
Number of pages3
JournalVox Sanguinis
Issue number4
Publication statusPublished - Jan 1 1986


All Science Journal Classification (ASJC) codes

  • Hematology

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