Emerging molecular approaches in stem cell biology

Amritha Jaishankar, Kent E. Vrana

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Stem cells are characterized by their ability to self-renew and differentiate into multiple adult cell types. Although substantial progress has been made over the last decade in understanding stem cell biology, recent technological advances in molecular and systems biology may hold the key to unraveling the mystery behind stem cell self-renewal and plasticity. The most notable of these advances is the ability to generate induced pluripotent cells from somatic cells. In this review, we discuss our current understanding of molecular similarities and differences among various stem cell types. Moreover, we survey the current state of systems biology and forecast future needs and direction in the stem cell field.

Original languageEnglish (US)
Pages (from-to)367-371
Number of pages5
JournalBioTechniques
Volume46
Issue number5 SPEC. ISSUE
DOIs
StatePublished - Apr 2009

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Biochemistry, Genetics and Molecular Biology(all)

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