Enantioselective synthesis of the ent-lomaiviticin A bicyclic core

Ken S. Feldman, Brandon R. Selfridge

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

The bicyclic core of ent-lomaiviticin A was prepared in 11 operations from (S)-1-phenyl-2-propyn-1-ol in a two-directional route that features (1) a double Ireland Claisen rearrangement and (2) a double olefin metathesis reaction to form the key C-C bonds of the target.

Original languageEnglish (US)
Pages (from-to)5484-5487
Number of pages4
JournalOrganic Letters
Volume14
Issue number21
DOIs
StatePublished - Nov 2 2012

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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