Encapsulation of a compartmentalized cytoplasm mimic within a lipid membrane by microfluidics

Marta Sobrinos-Sanguino, Silvia Zorrilla, Christine D. Keating, Begoña Monterroso, Germán Rivas

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

There is growing interest in analyzing the effect of microenvironments, which may be mimicked through liquid-liquid phase separation (LLPS), on the reactivity of biological macromolecules. We report the encapsulation by microfluidics of the division protein FtsZ and a LLPS system inside microdroplets and their conversion into permeable vesicles (allowing ligand uptake), with higher yield, homogeneity and biomolecular compatibility than those previously described.

Original languageEnglish (US)
Pages (from-to)4775-4778
Number of pages4
JournalChemical Communications
Volume53
Issue number35
DOIs
StatePublished - Jan 1 2017

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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