25 Scopus citations

Abstract

Visceral leishmaniasis was diagnosed by cytology and positive indirect immunofluorescent antibody titers to Leishmania donovani in a 7‐month‐old female Basenji dog from Texas. Clinical and laboratory findings included weight loss, hematochezia, hyperglobulinemia, hypoalbuminemia, anemia, and neutrophilic leukocytosis. Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. Several foci of endemic leishmaniasis have been reported in the United States. Because of its zoonotic potential and the lack of approved treatments for dogs with leishmaniasis in the United States, the development of effective treatment strategies is needed.

Original languageEnglish (US)
Pages (from-to)16-19
Number of pages4
JournalJournal of Veterinary Internal Medicine
Volume7
Issue number1
DOIs
StatePublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • veterinary(all)

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    Sellon, R. K., Menard, M. M., Meuten, D. J., Lengerich, E., Steurer, F. J., & Breitschwerdt, E. B. (1993). Endemic Visceral Leishmaniasis in a Dog from Texas. Journal of Veterinary Internal Medicine, 7(1), 16-19. https://doi.org/10.1111/j.1939-1676.1993.tb03163.x