Endocarditis due to coagulase-negative staphylococci: Microbiologic, epidemiologic, and clinical considerations

C. Whitener, G. M. Caputo, M. R. Weitekamp, A. W. Karchmer

Research output: Contribution to journalReview article

62 Scopus citations

Abstract

Coagulase-negative staphylococci are the most frequently isolated pathogens in prosthetic valve endocarditis and cause 5% of infections involving native valves. Distinguishing contamination from bacteremia may be challenging. The presence of heteroresistance in many strains makes rigorous susceptibility testing a requirement for selecting appropriate antibiotic selection. Infection is frequently complicated by valvular insufficiency with congestive heart failure, local tissue invasion or synthetic embolization, making surgical intervention necessary in many cases.

Original languageEnglish (US)
Pages (from-to)81-96
Number of pages16
JournalInfectious Disease Clinics of North America
Volume7
Issue number1
StatePublished - Jan 1 1993

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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