Endometrial antibodies versus CA-125 for the detection of endometriosis

R. A. Wild, V. Hirisave, A. Bianco, E. S. Podczaski, L. M. Demers

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Detection of endometrial antibodies using an indirect immunofluorescence method along with a well-established human endometrial carcinoma cell line was evaluated and compared with CA-125 for detecting endometriosis. Two hundred two patient sera from the infertility, gynecological, and gynecological oncology services were evaluated. The sensitivity for antibody testing was 83.1% with a specificity of 78.8%, in contrast to a sensitivity of 27.3% and a specificity of 82.6% for CA-125. These preliminary findings offer promise that antibody detection methods may be a useful adjunct in the diagnosis of endometriosis.

Original languageEnglish (US)
Pages (from-to)90-94
Number of pages5
JournalFertility and sterility
Issue number1
StatePublished - 1991

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynecology


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