Endophthalmitis associated with deep corneal infections

Ingrid Scott, H. W. Flynn, S. C. Pflugfelder, E. Alfonso, R. K. Forster

Research output: Contribution to journalArticle

Abstract

Purpose. To investigate risk factors, causative organisms, and visual outcomes of endophthalmitis associated with deep corneal infections. Methods. Clinical records and laboratory reports of all patients with both a positive corneal and a positive intraocular culture at the Bascom Palmer Eye Institute between January 1, 1990, and March 31, 1995, were reviewed. Results. Fourteen patients were identified. Thirteen patients had a recent history of corticosteroid use, and five patients were being treated for a systemic condition associated with impaired immune function. Eight patients had a history of previous ocular surgery. Gram-negative organisms (7) were the most frequently isolated bacteria; fungi (4) were also isolated. After treatment, six patients achieved a visual acuity of 20/200 or better. Conclusions. Patients who develop endophthalmitis associated with deep corneal infections have a frequent history of corticosteroid use, systemic conditions associated with impaired immune function, and previous ocular surgery. In general, the causative agents consist of organisms less frequently reported to be etiological agents in series of postoperative and posttraumatic endophthalmitis. The post-treatment visual acuity outcomes were generally poor.

Original languageEnglish (US)
JournalInvestigative Ophthalmology and Visual Science
Volume37
Issue number3
StatePublished - Feb 15 1996

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Endophthalmitis
Infection
Visual Acuity
Adrenal Cortex Hormones
Fungi
Bacteria
Therapeutics

All Science Journal Classification (ASJC) codes

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Scott, I., Flynn, H. W., Pflugfelder, S. C., Alfonso, E., & Forster, R. K. (1996). Endophthalmitis associated with deep corneal infections. Investigative Ophthalmology and Visual Science, 37(3).
Scott, Ingrid ; Flynn, H. W. ; Pflugfelder, S. C. ; Alfonso, E. ; Forster, R. K. / Endophthalmitis associated with deep corneal infections. In: Investigative Ophthalmology and Visual Science. 1996 ; Vol. 37, No. 3.
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Scott, I, Flynn, HW, Pflugfelder, SC, Alfonso, E & Forster, RK 1996, 'Endophthalmitis associated with deep corneal infections', Investigative Ophthalmology and Visual Science, vol. 37, no. 3.

Endophthalmitis associated with deep corneal infections. / Scott, Ingrid; Flynn, H. W.; Pflugfelder, S. C.; Alfonso, E.; Forster, R. K.

In: Investigative Ophthalmology and Visual Science, Vol. 37, No. 3, 15.02.1996.

Research output: Contribution to journalArticle

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AU - Flynn, H. W.

AU - Pflugfelder, S. C.

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AU - Forster, R. K.

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Scott I, Flynn HW, Pflugfelder SC, Alfonso E, Forster RK. Endophthalmitis associated with deep corneal infections. Investigative Ophthalmology and Visual Science. 1996 Feb 15;37(3).