Endothelial glycocalyx and cardiovascular disease

Ke Wen, Ping He, Jian Shi Lou

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Endothelial glycocalyx is a hairy-like structure covered the endothelial cell surface, which consists of multiple functional elements. It has been proved that glycocalyx can regulate vascular permeability, mediate shear-induced release of NO by endothelial cells, and exert wide array of vasculoprotective effects via inhibition of coagulation and leucocyte adhesion. Degradation of glycocalyx may be associated with many cardiovascular diseases. In this review, the relationship between the endothelial glycocalyx and cardiovascular disease will be discussed.

Original languageEnglish (US)
Pages (from-to)981-984
Number of pages4
JournalChinese Pharmacological Bulletin
Volume24
Issue number8
StatePublished - Jan 1 2008

All Science Journal Classification (ASJC) codes

  • Pharmacology

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