Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions

Xi Zhao, Krishna K. Dey, Selva Jeganathan, Peter J. Butler, Ubaldo M. Córdova-Figueroa, Ayusman Sen

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Colloidal suspensions containing microscopic swimmers have been the focus of recent studies aimed at understanding the principles of energy transfer in fluidic media at low Reynolds number conditions. Going down in scale, active enzymes have been shown to be force-generating, nonequilibrium systems, thus offering opportunity to examine energy transfer at the ultralow Reynolds number regime. By monitoring the change of diffusion of inert tracers dispersed in active enzyme solutions, we demonstrate that the nature of energy transfer in these systems is similar to that reported for larger microscopic active systems, despite the large differences in scale, modes of energy transduction, and propulsion. Additionally, even an enzyme that catalyzes an endothermic reaction behaves analogously, suggesting that heat generation is not the primary factor for the observed enhanced tracer diffusion. Our results provide new insights into the mechanism of energy transfer at the molecular level.

Original languageEnglish (US)
Pages (from-to)4807-4812
Number of pages6
JournalNano letters
Volume17
Issue number8
DOIs
StatePublished - Aug 9 2017

Fingerprint

Energy transfer
tracers
enzymes
Enzymes
energy transfer
Reynolds number
endothermic reactions
heat generation
fluidics
Heat generation
low Reynolds number
Fluidics
propulsion
Propulsion
colloids
Suspensions
Monitoring
energy

All Science Journal Classification (ASJC) codes

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

Cite this

Zhao, Xi ; Dey, Krishna K. ; Jeganathan, Selva ; Butler, Peter J. ; Córdova-Figueroa, Ubaldo M. ; Sen, Ayusman. / Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions. In: Nano letters. 2017 ; Vol. 17, No. 8. pp. 4807-4812.
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Zhao, X, Dey, KK, Jeganathan, S, Butler, PJ, Córdova-Figueroa, UM & Sen, A 2017, 'Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions', Nano letters, vol. 17, no. 8, pp. 4807-4812. https://doi.org/10.1021/acs.nanolett.7b01618

Enhanced Diffusion of Passive Tracers in Active Enzyme Solutions. / Zhao, Xi; Dey, Krishna K.; Jeganathan, Selva; Butler, Peter J.; Córdova-Figueroa, Ubaldo M.; Sen, Ayusman.

In: Nano letters, Vol. 17, No. 8, 09.08.2017, p. 4807-4812.

Research output: Contribution to journalArticle

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