Environmental Change, the Stress Response, and Neurogenesis

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Synopsis Previous to the 1980s, the prevailing neuroscience dogma held that no new neurons were produced in the brains of adult mammals. Now, we understand that the production of new neurons, or neurogenesis, is a common and plastic process in the adult brain. To date, however, researchers have not come to a unified understanding of the functional significance of neurogenesis. Several factors have been shown to modulate hippocampal neurogenesis including spatial learning, stress, and aspects of environmental change, but questions still remain. How do these modulating factors overlap? Which aspects of environmental change induce a stress response? Is there a relationship between hippocampal neurogenesis, the stress response, and environmental change? Can this relationship be altered when taking into consideration other factors such as perception and predictability of the environment? Finally, do results from neurobiological research on laboratory rodents translate to wild systems? This review attempts to address these questions and synthesize research from the fields of ecology, psychology, and behavioral neuroscience.

Original languageEnglish (US)
Pages (from-to)373-383
Number of pages11
JournalIntegrative and comparative biology
Volume55
Issue number3
DOIs
StatePublished - Sep 1 2015

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neurogenesis
stress response
neurophysiology
neurons
brain
psychology
rodents
learning
plastics
researchers
mammals
ecology

All Science Journal Classification (ASJC) codes

  • Animal Science and Zoology
  • Plant Science

Cite this

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abstract = "Synopsis Previous to the 1980s, the prevailing neuroscience dogma held that no new neurons were produced in the brains of adult mammals. Now, we understand that the production of new neurons, or neurogenesis, is a common and plastic process in the adult brain. To date, however, researchers have not come to a unified understanding of the functional significance of neurogenesis. Several factors have been shown to modulate hippocampal neurogenesis including spatial learning, stress, and aspects of environmental change, but questions still remain. How do these modulating factors overlap? Which aspects of environmental change induce a stress response? Is there a relationship between hippocampal neurogenesis, the stress response, and environmental change? Can this relationship be altered when taking into consideration other factors such as perception and predictability of the environment? Finally, do results from neurobiological research on laboratory rodents translate to wild systems? This review attempts to address these questions and synthesize research from the fields of ecology, psychology, and behavioral neuroscience.",
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Environmental Change, the Stress Response, and Neurogenesis. / Ladage, Lara D.

In: Integrative and comparative biology, Vol. 55, No. 3, 01.09.2015, p. 373-383.

Research output: Contribution to journalArticle

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