Esophageal lichen planus and hepatitis C

Review of the literature

Mohammad R. Taheri, Bryan Anderson, Thomas Riley III

Research output: Contribution to journalReview article

Abstract

Lichen planus (LP) is an inflammatory disease of autoimmune origin affecting the skin and mucosa with a population prevalence of 0.5%-1.5%. Esophageal involvement with LP is very rare. Oral LP has been associated with chronic liver disease, particularly Hepatitis C virus (HCV) infection. The treatment of hepatitis C, at present, is based on pegylated interferon (Peg-INF) and ribavirin. The relationship between LP and treatment of HCV remains uncertain. Some case series have indicated a worsening of oral lichen planus lesions during interferon based treatment but this association is not clear. In this paper, we report the first case in the literature of a patient with esophageal lichen planus related to HCV infection and provide a review of the pertinent world's literature.

Original languageEnglish (US)
Pages (from-to)33-40
Number of pages8
JournalPractical Gastroenterology
Volume32
Issue number1
StatePublished - Jan 1 2008

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Lichen Planus
Hepatitis C
Hepacivirus
Oral Lichen Planus
Virus Diseases
Interferons
Ribavirin
Autoimmune Diseases
Liver Diseases
Mucous Membrane
Chronic Disease
Therapeutics
Skin
Population

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

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title = "Esophageal lichen planus and hepatitis C: Review of the literature",
abstract = "Lichen planus (LP) is an inflammatory disease of autoimmune origin affecting the skin and mucosa with a population prevalence of 0.5{\%}-1.5{\%}. Esophageal involvement with LP is very rare. Oral LP has been associated with chronic liver disease, particularly Hepatitis C virus (HCV) infection. The treatment of hepatitis C, at present, is based on pegylated interferon (Peg-INF) and ribavirin. The relationship between LP and treatment of HCV remains uncertain. Some case series have indicated a worsening of oral lichen planus lesions during interferon based treatment but this association is not clear. In this paper, we report the first case in the literature of a patient with esophageal lichen planus related to HCV infection and provide a review of the pertinent world's literature.",
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Esophageal lichen planus and hepatitis C : Review of the literature. / Taheri, Mohammad R.; Anderson, Bryan; Riley III, Thomas.

In: Practical Gastroenterology, Vol. 32, No. 1, 01.01.2008, p. 33-40.

Research output: Contribution to journalReview article

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