Estimates of the half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in vietnam veterans of operation ranch hand

James L. Pirkle, William H. Wolfe, Donald George Jr Patterson, Larry L. Needham, Joel E. Michalek, Judson C. Miner, Michael R. Peterson, Donald L. Phillips

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Abstract

The half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (2, 3, 7, 8-TCDD; commonly known as dioxin) in serum has been measured in 36 Air Force Vietnam veterans of Operation Ranch Hand, which was the operation that aerially sprayed the herbicide Agent Orange in Vietnam. From serum specimens taken in 1982 and 1987, the median half-life of 2, 3, 7, 8-TCDD in these Ranch Hand veterans was found to be 7.1 yr (95% confidence.

Original languageEnglish (US)
Pages (from-to)165-171
Number of pages7
JournalJournal of Toxicology and Environmental Health
Volume27
Issue number2
DOIs
StatePublished - Jun 1 1989

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All Science Journal Classification (ASJC) codes

  • Toxicology
  • Pollution

Cite this

Pirkle, J. L., Wolfe, W. H., Patterson, D. G. J., Needham, L. L., Michalek, J. E., Miner, J. C., Peterson, M. R., & Phillips, D. L. (1989). Estimates of the half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in vietnam veterans of operation ranch hand. Journal of Toxicology and Environmental Health, 27(2), 165-171. https://doi.org/10.1080/15287398909531288