Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field

Meng Wang, Jiang Wang, Chenhui Jia, Xile Wei, Bin Deng, Yanqiu Che

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

As a universal phenomenon in neural system, synchronization has attracted more attention in recent years. Moreover, synchronization control in neural system is considered as a method of curing mental diseases. However, the unknown factor in neural system may bring difficulties in the designation of controllers. In this paper, based on Lyapunov theory, we create a 'neuron observer' to control an abnormal neuron with unknown abnormal parameters, and transform the control signal to the external electric field to make the method available in clinical practice. According to the simulation result, this control strategy can accurately estimate the parameters in the reference neuron, and the character of the abnormal neuron can be accurately adjusted to normal condition. This method can be used as a potential therapy of mental diseases caused by abnormal changes of parameters in neural system.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Chinese Control Conference, CCC 2012
Pages7403-7407
Number of pages5
StatePublished - Dec 1 2012
Event31st Chinese Control Conference, CCC 2012 - Hefei, China
Duration: Jul 25 2012Jul 27 2012

Publication series

NameChinese Control Conference, CCC
ISSN (Print)1934-1768
ISSN (Electronic)2161-2927

Other

Other31st Chinese Control Conference, CCC 2012
CountryChina
CityHefei
Period7/25/127/27/12

Fingerprint

External Field
Neurons
Neuron
Electric Field
Electric fields
Synchronization
Lyapunov Theory
Curing
Signal Control
Unknown Parameters
Therapy
Control Strategy
Observer
Transform
Controller
Unknown
Controllers
Estimate
Simulation

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Control and Systems Engineering
  • Applied Mathematics
  • Modeling and Simulation

Cite this

Wang, M., Wang, J., Jia, C., Wei, X., Deng, B., & Che, Y. (2012). Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field. In Proceedings of the 31st Chinese Control Conference, CCC 2012 (pp. 7403-7407). [6391251] (Chinese Control Conference, CCC).
Wang, Meng ; Wang, Jiang ; Jia, Chenhui ; Wei, Xile ; Deng, Bin ; Che, Yanqiu. / Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field. Proceedings of the 31st Chinese Control Conference, CCC 2012. 2012. pp. 7403-7407 (Chinese Control Conference, CCC).
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Wang, M, Wang, J, Jia, C, Wei, X, Deng, B & Che, Y 2012, Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field. in Proceedings of the 31st Chinese Control Conference, CCC 2012., 6391251, Chinese Control Conference, CCC, pp. 7403-7407, 31st Chinese Control Conference, CCC 2012, Hefei, China, 7/25/12.

Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field. / Wang, Meng; Wang, Jiang; Jia, Chenhui; Wei, Xile; Deng, Bin; Che, Yanqiu.

Proceedings of the 31st Chinese Control Conference, CCC 2012. 2012. p. 7403-7407 6391251 (Chinese Control Conference, CCC).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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AB - As a universal phenomenon in neural system, synchronization has attracted more attention in recent years. Moreover, synchronization control in neural system is considered as a method of curing mental diseases. However, the unknown factor in neural system may bring difficulties in the designation of controllers. In this paper, based on Lyapunov theory, we create a 'neuron observer' to control an abnormal neuron with unknown abnormal parameters, and transform the control signal to the external electric field to make the method available in clinical practice. According to the simulation result, this control strategy can accurately estimate the parameters in the reference neuron, and the character of the abnormal neuron can be accurately adjusted to normal condition. This method can be used as a potential therapy of mental diseases caused by abnormal changes of parameters in neural system.

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Wang M, Wang J, Jia C, Wei X, Deng B, Che Y. Estimating and adjusting the abnormal hodgkin-huxley neuron with external electric field. In Proceedings of the 31st Chinese Control Conference, CCC 2012. 2012. p. 7403-7407. 6391251. (Chinese Control Conference, CCC).