Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities

Xiaojie Wang, Zhengmin Qian, Xiaojie Wang, Hua Hong, Yin Yang, Yanjun Xu, Xiaojun Xu, Zhenjiang Yao, Lingli Zhang, Craig A. Rolling, Mario Schootman, Tao Liu, Jianpeng Xiao, Xing Li, Weilin Zeng, Wenjun Ma, Hualiang Lin

Research output: Contribution to journalArticle

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Abstract

While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 μg/m3 increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88% (95% CI: 1.37%, 2.39%), 3.07% (95% CI: 2.35%, 3.79%), and 5.72% (95% CI: 3.82%, 7.65%) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21% (95% CI: 1.65%, 3.01%) of stroke mortality (corresponding to 1743 stroke mortalities, 95% CI: 896, 1633) were attributed to PM10, 5.57% (95% CI: 0.50%, 1.23%) stroke mortality (3019, 95% CI: 2286, 3777) were attributed to PM2.5, and 2.02% (95% CI: 1.85%, 3.08%) of stroke mortality (1097, 95% CI: 1005, 1673) could be attributed to PM10-2.5. Our analysis indicates that both PM2.5 and PM10-2.5 are important risk factors of stroke mortality and should be considered in the prevention and control of stroke in the study area.

Original languageEnglish (US)
Pages (from-to)812-817
Number of pages6
JournalEnvironmental Pollution
Volume239
DOIs
StatePublished - Aug 2018

Fingerprint

Pollution
Stroke
Health
Mortality
Cerebrovascular Disorders
Meta-Analysis
Guidelines

All Science Journal Classification (ASJC) codes

  • Toxicology
  • Pollution
  • Health, Toxicology and Mutagenesis

Cite this

Wang, Xiaojie ; Qian, Zhengmin ; Wang, Xiaojie ; Hong, Hua ; Yang, Yin ; Xu, Yanjun ; Xu, Xiaojun ; Yao, Zhenjiang ; Zhang, Lingli ; Rolling, Craig A. ; Schootman, Mario ; Liu, Tao ; Xiao, Jianpeng ; Li, Xing ; Zeng, Weilin ; Ma, Wenjun ; Lin, Hualiang. / Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities. In: Environmental Pollution. 2018 ; Vol. 239. pp. 812-817.
@article{cb02026c251240b3a751b6ef51c818d8,
title = "Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities",
abstract = "While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 μg/m3 increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88{\%} (95{\%} CI: 1.37{\%}, 2.39{\%}), 3.07{\%} (95{\%} CI: 2.35{\%}, 3.79{\%}), and 5.72{\%} (95{\%} CI: 3.82{\%}, 7.65{\%}) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21{\%} (95{\%} CI: 1.65{\%}, 3.01{\%}) of stroke mortality (corresponding to 1743 stroke mortalities, 95{\%} CI: 896, 1633) were attributed to PM10, 5.57{\%} (95{\%} CI: 0.50{\%}, 1.23{\%}) stroke mortality (3019, 95{\%} CI: 2286, 3777) were attributed to PM2.5, and 2.02{\%} (95{\%} CI: 1.85{\%}, 3.08{\%}) of stroke mortality (1097, 95{\%} CI: 1005, 1673) could be attributed to PM10-2.5. Our analysis indicates that both PM2.5 and PM10-2.5 are important risk factors of stroke mortality and should be considered in the prevention and control of stroke in the study area.",
author = "Xiaojie Wang and Zhengmin Qian and Xiaojie Wang and Hua Hong and Yin Yang and Yanjun Xu and Xiaojun Xu and Zhenjiang Yao and Lingli Zhang and Rolling, {Craig A.} and Mario Schootman and Tao Liu and Jianpeng Xiao and Xing Li and Weilin Zeng and Wenjun Ma and Hualiang Lin",
year = "2018",
month = "8",
doi = "10.1016/j.envpol.2018.04.102",
language = "English (US)",
volume = "239",
pages = "812--817",
journal = "Environmental Pollution",
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Wang, X, Qian, Z, Wang, X, Hong, H, Yang, Y, Xu, Y, Xu, X, Yao, Z, Zhang, L, Rolling, CA, Schootman, M, Liu, T, Xiao, J, Li, X, Zeng, W, Ma, W & Lin, H 2018, 'Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities', Environmental Pollution, vol. 239, pp. 812-817. https://doi.org/10.1016/j.envpol.2018.04.102

Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities. / Wang, Xiaojie; Qian, Zhengmin; Wang, Xiaojie; Hong, Hua; Yang, Yin; Xu, Yanjun; Xu, Xiaojun; Yao, Zhenjiang; Zhang, Lingli; Rolling, Craig A.; Schootman, Mario; Liu, Tao; Xiao, Jianpeng; Li, Xing; Zeng, Weilin; Ma, Wenjun; Lin, Hualiang.

In: Environmental Pollution, Vol. 239, 08.2018, p. 812-817.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Estimating the acute effects of fine and coarse particle pollution on stroke mortality of in six Chinese subtropical cities

AU - Wang, Xiaojie

AU - Qian, Zhengmin

AU - Wang, Xiaojie

AU - Hong, Hua

AU - Yang, Yin

AU - Xu, Yanjun

AU - Xu, Xiaojun

AU - Yao, Zhenjiang

AU - Zhang, Lingli

AU - Rolling, Craig A.

AU - Schootman, Mario

AU - Liu, Tao

AU - Xiao, Jianpeng

AU - Li, Xing

AU - Zeng, Weilin

AU - Ma, Wenjun

AU - Lin, Hualiang

PY - 2018/8

Y1 - 2018/8

N2 - While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 μg/m3 increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88% (95% CI: 1.37%, 2.39%), 3.07% (95% CI: 2.35%, 3.79%), and 5.72% (95% CI: 3.82%, 7.65%) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21% (95% CI: 1.65%, 3.01%) of stroke mortality (corresponding to 1743 stroke mortalities, 95% CI: 896, 1633) were attributed to PM10, 5.57% (95% CI: 0.50%, 1.23%) stroke mortality (3019, 95% CI: 2286, 3777) were attributed to PM2.5, and 2.02% (95% CI: 1.85%, 3.08%) of stroke mortality (1097, 95% CI: 1005, 1673) could be attributed to PM10-2.5. Our analysis indicates that both PM2.5 and PM10-2.5 are important risk factors of stroke mortality and should be considered in the prevention and control of stroke in the study area.

AB - While increasing evidence suggested that PM2.5 is the most harmful fraction of the particle pollutants, the health effects of coarse particles (PM10-2.5) have been inconclusive, especially on cerebrovascular diseases, we thus evaluated the effects of PM10, PM2.5, and PM10-2.5 on stroke mortality in six Chinese subtropical cities using generalized additive models. We also conducted random-effects meta-analyses to estimate the overall effects across the six cities. We found that PM10, PM2.5, and PM10-2.5 were significantly associated with stroke mortality. Each 10 μg/m3 increase of PM10, PM2.5 and PM10-2.5 (lag03) was associated with an increase of 1.88% (95% CI: 1.37%, 2.39%), 3.07% (95% CI: 2.35%, 3.79%), and 5.72% (95% CI: 3.82%, 7.65%) in overall stroke mortality. Using the World Health Organization's guideline as reference concentration, we estimated that 3.21% (95% CI: 1.65%, 3.01%) of stroke mortality (corresponding to 1743 stroke mortalities, 95% CI: 896, 1633) were attributed to PM10, 5.57% (95% CI: 0.50%, 1.23%) stroke mortality (3019, 95% CI: 2286, 3777) were attributed to PM2.5, and 2.02% (95% CI: 1.85%, 3.08%) of stroke mortality (1097, 95% CI: 1005, 1673) could be attributed to PM10-2.5. Our analysis indicates that both PM2.5 and PM10-2.5 are important risk factors of stroke mortality and should be considered in the prevention and control of stroke in the study area.

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U2 - 10.1016/j.envpol.2018.04.102

DO - 10.1016/j.envpol.2018.04.102

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JF - Environmental Pollution

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