Estimation of individual genetic and environmental factor scores

D. I. Boomsma, P. C.M. Molenaar, J. F. Orlebeke

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Implicit in the application of the common‐factor model as a method for decomposing trait covariance into a genetic and environmental part is the use of factor scores. In multivariate analyses, it is possible to estimate these factor scores for the communal part of the model. Estimation of scores on latent factors in terms of individual observations within the context of a twin/family study amounts to estimation of individual genetic and environmental scores. Such estimates may be of both theoretical and practical interest and may be provided with confidence intervals around the individual estimates. The method is first illustrated with simulated twin data and next is applied to blood pressure data obtained in a Dutch sample of 59 male adolescent twin pairs. Subjects with high blood pressure can be distinguished into groups with high genetic or high environmental scores.

Original languageEnglish (US)
Pages (from-to)83-91
Number of pages9
JournalGenetic Epidemiology
Volume7
Issue number1
DOIs
StatePublished - Jan 1 1990

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'Estimation of individual genetic and environmental factor scores'. Together they form a unique fingerprint.

  • Cite this