Evaluation of preterm delivery in a systemic lupus erythematosus pregnancy clinic

Mary Jo Johnson, Michelle Petri, Frank R. Witter, John Repke

Research output: Contribution to journalArticle

67 Citations (Scopus)

Abstract

Objective: To identify the primary etiology of preterm birth in women with systemic lupus erythematosus, analyzing prospective data collected on 66 pregnancies in 58 women followed-up at a lupus pregnancy center. Methods: Hospital records were reviewed and subjects were interviewed for pregnancies delivered after 23 completed weeks' gestation in women cared for at the Hopkins Lupus Pregnancy Center. A control group consisted of all women delivered at the same hospital during 2 years of the study period. Results: Preterm premature rupture of membranes (PROM) occurred in 13 of 33 (39%) pregnancies delivered at 24-36 weeks' gestation. In addition, term PROM also occurred with high incidence in ten of 33 (30.3%) pregnancies delivered after 36 weeks' gestation. The rate of PROM in study subjects differed from that in controls at 34-36 weeks' gestation and after 36 weeks. Conclusion: Premature rupture of membranes is more common in pregnancies occurring in women with systemic lupus erythematosus than in control pregnancies. Disease activity, prednisone use, and serologic studies are not predictive. Premature rupture of membranes is the major etiology of preterm birth in this cohort.

Original languageEnglish (US)
Pages (from-to)396-399
Number of pages4
JournalObstetrics and Gynecology
Volume86
Issue number3
DOIs
StatePublished - Jan 1 1995

Fingerprint

Systemic Lupus Erythematosus
Pregnancy
Rupture
Membranes
Premature Birth
Hospital Records
Prednisone
Control Groups

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynecology

Cite this

Johnson, Mary Jo ; Petri, Michelle ; Witter, Frank R. ; Repke, John. / Evaluation of preterm delivery in a systemic lupus erythematosus pregnancy clinic. In: Obstetrics and Gynecology. 1995 ; Vol. 86, No. 3. pp. 396-399.
@article{0fb2a71ee7984fcf9453c2c0f6783941,
title = "Evaluation of preterm delivery in a systemic lupus erythematosus pregnancy clinic",
abstract = "Objective: To identify the primary etiology of preterm birth in women with systemic lupus erythematosus, analyzing prospective data collected on 66 pregnancies in 58 women followed-up at a lupus pregnancy center. Methods: Hospital records were reviewed and subjects were interviewed for pregnancies delivered after 23 completed weeks' gestation in women cared for at the Hopkins Lupus Pregnancy Center. A control group consisted of all women delivered at the same hospital during 2 years of the study period. Results: Preterm premature rupture of membranes (PROM) occurred in 13 of 33 (39{\%}) pregnancies delivered at 24-36 weeks' gestation. In addition, term PROM also occurred with high incidence in ten of 33 (30.3{\%}) pregnancies delivered after 36 weeks' gestation. The rate of PROM in study subjects differed from that in controls at 34-36 weeks' gestation and after 36 weeks. Conclusion: Premature rupture of membranes is more common in pregnancies occurring in women with systemic lupus erythematosus than in control pregnancies. Disease activity, prednisone use, and serologic studies are not predictive. Premature rupture of membranes is the major etiology of preterm birth in this cohort.",
author = "Johnson, {Mary Jo} and Michelle Petri and Witter, {Frank R.} and John Repke",
year = "1995",
month = "1",
day = "1",
doi = "10.1016/0029-7844(95)00186-U",
language = "English (US)",
volume = "86",
pages = "396--399",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

Evaluation of preterm delivery in a systemic lupus erythematosus pregnancy clinic. / Johnson, Mary Jo; Petri, Michelle; Witter, Frank R.; Repke, John.

In: Obstetrics and Gynecology, Vol. 86, No. 3, 01.01.1995, p. 396-399.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Evaluation of preterm delivery in a systemic lupus erythematosus pregnancy clinic

AU - Johnson, Mary Jo

AU - Petri, Michelle

AU - Witter, Frank R.

AU - Repke, John

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Objective: To identify the primary etiology of preterm birth in women with systemic lupus erythematosus, analyzing prospective data collected on 66 pregnancies in 58 women followed-up at a lupus pregnancy center. Methods: Hospital records were reviewed and subjects were interviewed for pregnancies delivered after 23 completed weeks' gestation in women cared for at the Hopkins Lupus Pregnancy Center. A control group consisted of all women delivered at the same hospital during 2 years of the study period. Results: Preterm premature rupture of membranes (PROM) occurred in 13 of 33 (39%) pregnancies delivered at 24-36 weeks' gestation. In addition, term PROM also occurred with high incidence in ten of 33 (30.3%) pregnancies delivered after 36 weeks' gestation. The rate of PROM in study subjects differed from that in controls at 34-36 weeks' gestation and after 36 weeks. Conclusion: Premature rupture of membranes is more common in pregnancies occurring in women with systemic lupus erythematosus than in control pregnancies. Disease activity, prednisone use, and serologic studies are not predictive. Premature rupture of membranes is the major etiology of preterm birth in this cohort.

AB - Objective: To identify the primary etiology of preterm birth in women with systemic lupus erythematosus, analyzing prospective data collected on 66 pregnancies in 58 women followed-up at a lupus pregnancy center. Methods: Hospital records were reviewed and subjects were interviewed for pregnancies delivered after 23 completed weeks' gestation in women cared for at the Hopkins Lupus Pregnancy Center. A control group consisted of all women delivered at the same hospital during 2 years of the study period. Results: Preterm premature rupture of membranes (PROM) occurred in 13 of 33 (39%) pregnancies delivered at 24-36 weeks' gestation. In addition, term PROM also occurred with high incidence in ten of 33 (30.3%) pregnancies delivered after 36 weeks' gestation. The rate of PROM in study subjects differed from that in controls at 34-36 weeks' gestation and after 36 weeks. Conclusion: Premature rupture of membranes is more common in pregnancies occurring in women with systemic lupus erythematosus than in control pregnancies. Disease activity, prednisone use, and serologic studies are not predictive. Premature rupture of membranes is the major etiology of preterm birth in this cohort.

UR - http://www.scopus.com/inward/record.url?scp=0029157155&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029157155&partnerID=8YFLogxK

U2 - 10.1016/0029-7844(95)00186-U

DO - 10.1016/0029-7844(95)00186-U

M3 - Article

C2 - 7651650

AN - SCOPUS:0029157155

VL - 86

SP - 396

EP - 399

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 3

ER -