Evaluation of the growth hormone exercise test in normal and growth hormone deficient children

E. Eisenstein, L. Plotnick, R. Lanes, P. A. Lee, C. J. Migeon, A. A. Kowarski

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Abstract

A group of 168 short but otherwise normal children (group A) and 25 children deficient in growth hormone (GH) (group B) were studied with an exercise stimulation test to determine the expected error of this method. In group A, 125 (74.4%) had maximum GH responses greater than 15 ng/ml, 23 (13.7%) had responses between 10 and 15 ng/ml, and 20 (11.9%) had responses less than 10 ng/ml. The mean ± SD values were 8.4 ± 0.4 ng/ml at 0 time, 26.3 ± 15.0 at 20 min, and 10.7 ± 8.3 at 40 min. The mean maximum response was 27.7 ± 14.3 ng/ml. In group B, 22 (88%) had maximum responses less than 10 ng/ml and 3 (12%) had responses between 10 and 15 ng/ml. Patients with maximum responses less than 10 ng/ml have a high probability of being GH deficient, whereas patients with responses between 10 and 15 ng/ml are less likely to be GH deficient. No patients with responses greater than 15 ng/ml were GH deficient.

Original languageEnglish (US)
Pages (from-to)526-528
Number of pages3
JournalPediatrics
Volume62
Issue number4
StatePublished - Dec 15 1978

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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    Eisenstein, E., Plotnick, L., Lanes, R., Lee, P. A., Migeon, C. J., & Kowarski, A. A. (1978). Evaluation of the growth hormone exercise test in normal and growth hormone deficient children. Pediatrics, 62(4), 526-528.