Evidence-based recommendations for the management of acne fulminans and its variants

Tanya Greywal, Andrea L. Zaenglein, Hilary E. Baldwin, Neal Bhatia, Karen A. Chernoff, James Q. Del Rosso, Lawrence F. Eichenfield, Marc H. Levin, James J. Leyden, Diane M. Thiboutot, Guy F. Webster, Sheila Fallon Friedlander

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Background Acne fulminans (AF) is a severe variant of inflammatory acne. It typically manifests as an explosive worsening and ulceration of skin lesions, and can be associated with systemic symptoms. However, there is a paucity of evidence-based information and no clear guidelines concerning the classification and treatment of AF. Objective To better define the spectrum of AF and its variants, devise optimal therapeutic approaches, and identify areas of future research. Methods A panel of physicians with expertise in severe acne vulgaris was convened after a comprehensive literature review of severe acne variants. Priority topics were reviewed and presented by each panelist at a 5-hour conference. Following review of the audiotape and scribed notes from the conference, surveys were utilized to address points of controversy and to clarify consensus recommendations. Results Appropriate clinical case presentations and consensus survey questions were utilized to create final recommendations based on both the literature and the expert consensus. Limitations Limited evidenced-based data and prospective studies in the literature concerning the treatment of AF is available. Conclusion These guidelines better characterize AF and provide health care practitioners approaches to the classification, treatment, and prevention of AF and its variants.

Original languageEnglish (US)
Pages (from-to)109-117
Number of pages9
JournalJournal of the American Academy of Dermatology
Volume77
Issue number1
DOIs
StatePublished - Jul 1 2017

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Acne Vulgaris
Guidelines
Tape Recording
Therapeutics
Prospective Studies
Delivery of Health Care
Physicians
Skin

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Greywal, T., Zaenglein, A. L., Baldwin, H. E., Bhatia, N., Chernoff, K. A., Del Rosso, J. Q., ... Friedlander, S. F. (2017). Evidence-based recommendations for the management of acne fulminans and its variants. Journal of the American Academy of Dermatology, 77(1), 109-117. https://doi.org/10.1016/j.jaad.2016.11.028
Greywal, Tanya ; Zaenglein, Andrea L. ; Baldwin, Hilary E. ; Bhatia, Neal ; Chernoff, Karen A. ; Del Rosso, James Q. ; Eichenfield, Lawrence F. ; Levin, Marc H. ; Leyden, James J. ; Thiboutot, Diane M. ; Webster, Guy F. ; Friedlander, Sheila Fallon. / Evidence-based recommendations for the management of acne fulminans and its variants. In: Journal of the American Academy of Dermatology. 2017 ; Vol. 77, No. 1. pp. 109-117.
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abstract = "Background Acne fulminans (AF) is a severe variant of inflammatory acne. It typically manifests as an explosive worsening and ulceration of skin lesions, and can be associated with systemic symptoms. However, there is a paucity of evidence-based information and no clear guidelines concerning the classification and treatment of AF. Objective To better define the spectrum of AF and its variants, devise optimal therapeutic approaches, and identify areas of future research. Methods A panel of physicians with expertise in severe acne vulgaris was convened after a comprehensive literature review of severe acne variants. Priority topics were reviewed and presented by each panelist at a 5-hour conference. Following review of the audiotape and scribed notes from the conference, surveys were utilized to address points of controversy and to clarify consensus recommendations. Results Appropriate clinical case presentations and consensus survey questions were utilized to create final recommendations based on both the literature and the expert consensus. Limitations Limited evidenced-based data and prospective studies in the literature concerning the treatment of AF is available. Conclusion These guidelines better characterize AF and provide health care practitioners approaches to the classification, treatment, and prevention of AF and its variants.",
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Greywal, T, Zaenglein, AL, Baldwin, HE, Bhatia, N, Chernoff, KA, Del Rosso, JQ, Eichenfield, LF, Levin, MH, Leyden, JJ, Thiboutot, DM, Webster, GF & Friedlander, SF 2017, 'Evidence-based recommendations for the management of acne fulminans and its variants', Journal of the American Academy of Dermatology, vol. 77, no. 1, pp. 109-117. https://doi.org/10.1016/j.jaad.2016.11.028

Evidence-based recommendations for the management of acne fulminans and its variants. / Greywal, Tanya; Zaenglein, Andrea L.; Baldwin, Hilary E.; Bhatia, Neal; Chernoff, Karen A.; Del Rosso, James Q.; Eichenfield, Lawrence F.; Levin, Marc H.; Leyden, James J.; Thiboutot, Diane M.; Webster, Guy F.; Friedlander, Sheila Fallon.

In: Journal of the American Academy of Dermatology, Vol. 77, No. 1, 01.07.2017, p. 109-117.

Research output: Contribution to journalArticle

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T1 - Evidence-based recommendations for the management of acne fulminans and its variants

AU - Greywal, Tanya

AU - Zaenglein, Andrea L.

AU - Baldwin, Hilary E.

AU - Bhatia, Neal

AU - Chernoff, Karen A.

AU - Del Rosso, James Q.

AU - Eichenfield, Lawrence F.

AU - Levin, Marc H.

AU - Leyden, James J.

AU - Thiboutot, Diane M.

AU - Webster, Guy F.

AU - Friedlander, Sheila Fallon

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Background Acne fulminans (AF) is a severe variant of inflammatory acne. It typically manifests as an explosive worsening and ulceration of skin lesions, and can be associated with systemic symptoms. However, there is a paucity of evidence-based information and no clear guidelines concerning the classification and treatment of AF. Objective To better define the spectrum of AF and its variants, devise optimal therapeutic approaches, and identify areas of future research. Methods A panel of physicians with expertise in severe acne vulgaris was convened after a comprehensive literature review of severe acne variants. Priority topics were reviewed and presented by each panelist at a 5-hour conference. Following review of the audiotape and scribed notes from the conference, surveys were utilized to address points of controversy and to clarify consensus recommendations. Results Appropriate clinical case presentations and consensus survey questions were utilized to create final recommendations based on both the literature and the expert consensus. Limitations Limited evidenced-based data and prospective studies in the literature concerning the treatment of AF is available. Conclusion These guidelines better characterize AF and provide health care practitioners approaches to the classification, treatment, and prevention of AF and its variants.

AB - Background Acne fulminans (AF) is a severe variant of inflammatory acne. It typically manifests as an explosive worsening and ulceration of skin lesions, and can be associated with systemic symptoms. However, there is a paucity of evidence-based information and no clear guidelines concerning the classification and treatment of AF. Objective To better define the spectrum of AF and its variants, devise optimal therapeutic approaches, and identify areas of future research. Methods A panel of physicians with expertise in severe acne vulgaris was convened after a comprehensive literature review of severe acne variants. Priority topics were reviewed and presented by each panelist at a 5-hour conference. Following review of the audiotape and scribed notes from the conference, surveys were utilized to address points of controversy and to clarify consensus recommendations. Results Appropriate clinical case presentations and consensus survey questions were utilized to create final recommendations based on both the literature and the expert consensus. Limitations Limited evidenced-based data and prospective studies in the literature concerning the treatment of AF is available. Conclusion These guidelines better characterize AF and provide health care practitioners approaches to the classification, treatment, and prevention of AF and its variants.

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