Evolution of plant microRNAs and their targets

Michael Axtell, John L. Bowman

Research output: Contribution to journalReview article

258 Citations (Scopus)

Abstract

MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression. They have a limited phylogenetic distribution among eukaryotes, suggestive of at least two independent origins from an ancestral small RNA-producing pathway. A set of 21 abundantly expressed miRNAs are clearly conserved among the angiosperms; many of these function to regulate transcription factors involved in developmental control. Recent experiments have uncovered a much larger set of weakly expressed, less conserved miRNAs in plants, and this group has provided insights into the origins of miRNAs and their targets. These data have provided a coherent set of hypotheses explaining the birth, selection and death of miRNAs in land plants.

Original languageEnglish (US)
Pages (from-to)343-349
Number of pages7
JournalTrends in Plant Science
Volume13
Issue number7
DOIs
StatePublished - Jul 1 2008

Fingerprint

microRNA
embryophytes
RNA interference
eukaryotic cells
Angiospermae
transcription factors
RNA
death
gene expression
phylogeny

All Science Journal Classification (ASJC) codes

  • Plant Science

Cite this

Axtell, Michael ; Bowman, John L. / Evolution of plant microRNAs and their targets. In: Trends in Plant Science. 2008 ; Vol. 13, No. 7. pp. 343-349.
@article{1df201c9dbd6491ca446e59ccadf693a,
title = "Evolution of plant microRNAs and their targets",
abstract = "MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression. They have a limited phylogenetic distribution among eukaryotes, suggestive of at least two independent origins from an ancestral small RNA-producing pathway. A set of 21 abundantly expressed miRNAs are clearly conserved among the angiosperms; many of these function to regulate transcription factors involved in developmental control. Recent experiments have uncovered a much larger set of weakly expressed, less conserved miRNAs in plants, and this group has provided insights into the origins of miRNAs and their targets. These data have provided a coherent set of hypotheses explaining the birth, selection and death of miRNAs in land plants.",
author = "Michael Axtell and Bowman, {John L.}",
year = "2008",
month = "7",
day = "1",
doi = "10.1016/j.tplants.2008.03.009",
language = "English (US)",
volume = "13",
pages = "343--349",
journal = "Trends in Plant Science",
issn = "1360-1385",
publisher = "Elsevier Limited",
number = "7",

}

Evolution of plant microRNAs and their targets. / Axtell, Michael; Bowman, John L.

In: Trends in Plant Science, Vol. 13, No. 7, 01.07.2008, p. 343-349.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Evolution of plant microRNAs and their targets

AU - Axtell, Michael

AU - Bowman, John L.

PY - 2008/7/1

Y1 - 2008/7/1

N2 - MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression. They have a limited phylogenetic distribution among eukaryotes, suggestive of at least two independent origins from an ancestral small RNA-producing pathway. A set of 21 abundantly expressed miRNAs are clearly conserved among the angiosperms; many of these function to regulate transcription factors involved in developmental control. Recent experiments have uncovered a much larger set of weakly expressed, less conserved miRNAs in plants, and this group has provided insights into the origins of miRNAs and their targets. These data have provided a coherent set of hypotheses explaining the birth, selection and death of miRNAs in land plants.

AB - MicroRNAs (miRNAs) are a specialized class of small silencing RNAs that regulate gene expression. They have a limited phylogenetic distribution among eukaryotes, suggestive of at least two independent origins from an ancestral small RNA-producing pathway. A set of 21 abundantly expressed miRNAs are clearly conserved among the angiosperms; many of these function to regulate transcription factors involved in developmental control. Recent experiments have uncovered a much larger set of weakly expressed, less conserved miRNAs in plants, and this group has provided insights into the origins of miRNAs and their targets. These data have provided a coherent set of hypotheses explaining the birth, selection and death of miRNAs in land plants.

UR - http://www.scopus.com/inward/record.url?scp=43449118038&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43449118038&partnerID=8YFLogxK

U2 - 10.1016/j.tplants.2008.03.009

DO - 10.1016/j.tplants.2008.03.009

M3 - Review article

VL - 13

SP - 343

EP - 349

JO - Trends in Plant Science

JF - Trends in Plant Science

SN - 1360-1385

IS - 7

ER -