Evolutionary adaptations to dietary changess

F. Luca, G. H. Perry, A. Di Rienzo

Research output: Contribution to journalReview article

88 Citations (Scopus)

Abstract

Through cultural innovation and changes in habitat and ecology, there have been a number of major dietary shifts in human evolution, including meat eating, cooking, and those associated with plant and animal domestication. The identification of signatures of adaptations to such dietary changes in the genome of extant primates (including humans) may shed light not only on the evolutionary history of our species, but also on the mechanisms that underlie common metabolic diseases in modern human populations. In this review, we provide a brief overview of the major dietary shifts that occurred during hominin evolution, and we discuss the methods and approaches used to identify signals of natural selection in patterns of sequence variation. We then review the results of studies aimed at detecting the genetic loci that played a major role in dietary adaptations and conclude by outlining the potential of future studies in this area.

Original languageEnglish (US)
Pages (from-to)291-314
Number of pages24
JournalAnnual Review of Nutrition
Volume30
DOIs
StatePublished - Aug 21 2010

Fingerprint

Genetic Loci
Genetic Selection
Metabolic Diseases
Hominidae
Cooking
Ecology
Meat
Primates
Ecosystem
Eating
History
Genome
Population
Domestication

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Luca, F. ; Perry, G. H. ; Di Rienzo, A. / Evolutionary adaptations to dietary changess. In: Annual Review of Nutrition. 2010 ; Vol. 30. pp. 291-314.
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Evolutionary adaptations to dietary changess. / Luca, F.; Perry, G. H.; Di Rienzo, A.

In: Annual Review of Nutrition, Vol. 30, 21.08.2010, p. 291-314.

Research output: Contribution to journalReview article

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