Examining the relationship between computed tomography and neuropsychological measures in normal and demented elderly

Paul J. Eslinger, Hanna Damasio, Neill Graff-Radford, Antonio R. Damasio

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Correlational analysis of CT and neuropsychological measures in patients with dementia revealed more predictive relationships in degenerative and vascular subgroups that in a multi-aetiology group. Normal and dementia patients were then matched for age, sex and educational background, and analysed together. The ventricular/brain ratios of the bodies of the lateral ventricles and of the third ventricle correlated most highly with neuropsychologic performance. Canonical analysis revealed a correlation coefficient of 0O725 between the sets of CT and neuropsychological measures, which increased to 0-78 when a degenerative subgroup only was considered. Discriminant function analysis indicated that the combination of CT and neuropsychological measures was more powerful in discriminating normals from dementia patients than CT or neuropsychological measures alone.

Original languageEnglish (US)
Pages (from-to)1319-1325
Number of pages7
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume47
Issue number12
DOIs
StatePublished - 1984

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

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