Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise

Jill A. Bush, Kehchiro Dohi, Andrea M. Mastro, Jeff S. Volek, J. Michael Lynch, N. Travis Triplett-McBride, Margot Putukian, Wayne J. Sebastianelli, Robert U. Newton, Keijo Häkkinen, William J. Kraemer

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

To examine the effect of dynamic resistance exercise on the response patterns of lymphokines, 10 strength-trained men (21.7 ± 0.6 y) performed 2 resistance exercise protocols, high force (HF) and high power (HP), of equal total work (HF = 33.0 ± 2.5 kJ; HP = 33.3 ± 2.7 kJ) in a randomized order separated by 1 week. Resting blood samples were obtained preexercise and 0 (R-0), 15 (R-15), and 240 (R-240) minutes postexercise. Plasma lactate significantly (p < 0.05) increased from baseline for both protocols; however, concentrations were higher in response to the HF protocol. Plasma interleukin-2 (IL-2) concentrations were significantly decreased from baseline at R-15 following the HF protocol. Plasma interfer-on-gamma (IFN-γ) concentrations decreased at R-0 following the HP protocol and returned to preexercise levels by R-15. Although the suppression of these 2 lymphokines was transient, the results indicate that the acute stress of high force and high resistance workouts induce differential IFN-γ and IL-2 responses.

Original languageEnglish (US)
Pages (from-to)344-349
Number of pages6
JournalJournal of Strength and Conditioning Research
Volume14
Issue number3
DOIs
StatePublished - Jan 1 2000

Fingerprint

Lymphokines
Exercise
Interleukin-2
Lactic Acid

All Science Journal Classification (ASJC) codes

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Bush, J. A., Dohi, K., Mastro, A. M., Volek, J. S., Lynch, J. M., Triplett-McBride, N. T., ... Kraemer, W. J. (2000). Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise. Journal of Strength and Conditioning Research, 14(3), 344-349. https://doi.org/10.1519/00124278-200008000-00017
Bush, Jill A. ; Dohi, Kehchiro ; Mastro, Andrea M. ; Volek, Jeff S. ; Lynch, J. Michael ; Triplett-McBride, N. Travis ; Putukian, Margot ; Sebastianelli, Wayne J. ; Newton, Robert U. ; Häkkinen, Keijo ; Kraemer, William J. / Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise. In: Journal of Strength and Conditioning Research. 2000 ; Vol. 14, No. 3. pp. 344-349.
@article{5de17f0618934965911f826db425ded0,
title = "Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise",
abstract = "To examine the effect of dynamic resistance exercise on the response patterns of lymphokines, 10 strength-trained men (21.7 ± 0.6 y) performed 2 resistance exercise protocols, high force (HF) and high power (HP), of equal total work (HF = 33.0 ± 2.5 kJ; HP = 33.3 ± 2.7 kJ) in a randomized order separated by 1 week. Resting blood samples were obtained preexercise and 0 (R-0), 15 (R-15), and 240 (R-240) minutes postexercise. Plasma lactate significantly (p < 0.05) increased from baseline for both protocols; however, concentrations were higher in response to the HF protocol. Plasma interleukin-2 (IL-2) concentrations were significantly decreased from baseline at R-15 following the HF protocol. Plasma interfer-on-gamma (IFN-γ) concentrations decreased at R-0 following the HP protocol and returned to preexercise levels by R-15. Although the suppression of these 2 lymphokines was transient, the results indicate that the acute stress of high force and high resistance workouts induce differential IFN-γ and IL-2 responses.",
author = "Bush, {Jill A.} and Kehchiro Dohi and Mastro, {Andrea M.} and Volek, {Jeff S.} and Lynch, {J. Michael} and Triplett-McBride, {N. Travis} and Margot Putukian and Sebastianelli, {Wayne J.} and Newton, {Robert U.} and Keijo H{\"a}kkinen and Kraemer, {William J.}",
year = "2000",
month = "1",
day = "1",
doi = "10.1519/00124278-200008000-00017",
language = "English (US)",
volume = "14",
pages = "344--349",
journal = "Journal of Strength and Conditioning Research",
issn = "1064-8011",
publisher = "NSCA National Strength and Conditioning Association",
number = "3",

}

Bush, JA, Dohi, K, Mastro, AM, Volek, JS, Lynch, JM, Triplett-McBride, NT, Putukian, M, Sebastianelli, WJ, Newton, RU, Häkkinen, K & Kraemer, WJ 2000, 'Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise', Journal of Strength and Conditioning Research, vol. 14, no. 3, pp. 344-349. https://doi.org/10.1519/00124278-200008000-00017

Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise. / Bush, Jill A.; Dohi, Kehchiro; Mastro, Andrea M.; Volek, Jeff S.; Lynch, J. Michael; Triplett-McBride, N. Travis; Putukian, Margot; Sebastianelli, Wayne J.; Newton, Robert U.; Häkkinen, Keijo; Kraemer, William J.

In: Journal of Strength and Conditioning Research, Vol. 14, No. 3, 01.01.2000, p. 344-349.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Exercise and Recovery Responses of Lymphokines to Heavy Resistance Exercise

AU - Bush, Jill A.

AU - Dohi, Kehchiro

AU - Mastro, Andrea M.

AU - Volek, Jeff S.

AU - Lynch, J. Michael

AU - Triplett-McBride, N. Travis

AU - Putukian, Margot

AU - Sebastianelli, Wayne J.

AU - Newton, Robert U.

AU - Häkkinen, Keijo

AU - Kraemer, William J.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - To examine the effect of dynamic resistance exercise on the response patterns of lymphokines, 10 strength-trained men (21.7 ± 0.6 y) performed 2 resistance exercise protocols, high force (HF) and high power (HP), of equal total work (HF = 33.0 ± 2.5 kJ; HP = 33.3 ± 2.7 kJ) in a randomized order separated by 1 week. Resting blood samples were obtained preexercise and 0 (R-0), 15 (R-15), and 240 (R-240) minutes postexercise. Plasma lactate significantly (p < 0.05) increased from baseline for both protocols; however, concentrations were higher in response to the HF protocol. Plasma interleukin-2 (IL-2) concentrations were significantly decreased from baseline at R-15 following the HF protocol. Plasma interfer-on-gamma (IFN-γ) concentrations decreased at R-0 following the HP protocol and returned to preexercise levels by R-15. Although the suppression of these 2 lymphokines was transient, the results indicate that the acute stress of high force and high resistance workouts induce differential IFN-γ and IL-2 responses.

AB - To examine the effect of dynamic resistance exercise on the response patterns of lymphokines, 10 strength-trained men (21.7 ± 0.6 y) performed 2 resistance exercise protocols, high force (HF) and high power (HP), of equal total work (HF = 33.0 ± 2.5 kJ; HP = 33.3 ± 2.7 kJ) in a randomized order separated by 1 week. Resting blood samples were obtained preexercise and 0 (R-0), 15 (R-15), and 240 (R-240) minutes postexercise. Plasma lactate significantly (p < 0.05) increased from baseline for both protocols; however, concentrations were higher in response to the HF protocol. Plasma interleukin-2 (IL-2) concentrations were significantly decreased from baseline at R-15 following the HF protocol. Plasma interfer-on-gamma (IFN-γ) concentrations decreased at R-0 following the HP protocol and returned to preexercise levels by R-15. Although the suppression of these 2 lymphokines was transient, the results indicate that the acute stress of high force and high resistance workouts induce differential IFN-γ and IL-2 responses.

UR - http://www.scopus.com/inward/record.url?scp=0034414583&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034414583&partnerID=8YFLogxK

U2 - 10.1519/00124278-200008000-00017

DO - 10.1519/00124278-200008000-00017

M3 - Article

VL - 14

SP - 344

EP - 349

JO - Journal of Strength and Conditioning Research

JF - Journal of Strength and Conditioning Research

SN - 1064-8011

IS - 3

ER -