Experiences of cardiopulmonary bypass for heart transplantation

Fei Long Hei, Shi Gang Wang, Cun Long

Research output: Contribution to journalArticle

Abstract

Objective: To summarize the experiences of cardiopulmonary bypass (CPB) techniques in 15 patients of orthotopic heart transplantation. Methods: All patients received mild hypothermia and high flow rate perfusion. Effective strategies were taken to protect myocardium, lung, kidney, and blood conservation. The donor hearts were arrested with aorto perfusion using 1 000 ml St. Thomas solution at 4°C, perfused with 1 000 ml University of Wiscosin (UW) solution or Histidin-Tryptophan-Ketoglutarat (HTK) solution at 4°C, and then preserved in ice saline. Ice mud was covered on the donor heart during anastomosis. Low potassium cardioplegia solution was perfused before the unclamping of aorta. Results: The CPB time was (165.2 ± 22.8) min, the warm ischemia time was (7.7 ± 1.7) min, and the cold ischemia time was (142.4 ± 11.5) min. Heart beats was automatically recovered in 10 patients, and was recovered upon defibrillation in 5 patients. Left ventricular ejection fractions were (64.1 ± 4.6)% after one month. All patients survived. Conclusion: Proper CPB management and effective donor heart protection are essential to guarantee the success of heart transplantations.

Original languageEnglish (US)
Pages (from-to)228-231
Number of pages4
JournalActa Academiae Medicinae Sinicae
Volume29
Issue number2
StatePublished - Apr 1 2007

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Heart Transplantation
Cardiopulmonary Bypass
Ice
Tissue Donors
Perfusion
Cold Ischemia
Warm Ischemia
Induced Heart Arrest
Hypothermia
Tryptophan
Stroke Volume
Aorta
Myocardium
Potassium
Kidney
Lung

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Hei, F. L., Wang, S. G., & Long, C. (2007). Experiences of cardiopulmonary bypass for heart transplantation. Acta Academiae Medicinae Sinicae, 29(2), 228-231.
Hei, Fei Long ; Wang, Shi Gang ; Long, Cun. / Experiences of cardiopulmonary bypass for heart transplantation. In: Acta Academiae Medicinae Sinicae. 2007 ; Vol. 29, No. 2. pp. 228-231.
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Hei, FL, Wang, SG & Long, C 2007, 'Experiences of cardiopulmonary bypass for heart transplantation', Acta Academiae Medicinae Sinicae, vol. 29, no. 2, pp. 228-231.

Experiences of cardiopulmonary bypass for heart transplantation. / Hei, Fei Long; Wang, Shi Gang; Long, Cun.

In: Acta Academiae Medicinae Sinicae, Vol. 29, No. 2, 01.04.2007, p. 228-231.

Research output: Contribution to journalArticle

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