Abstract
Objective: To summarize the experiences of cardiopulmonary bypass (CPB) techniques in 15 patients of orthotopic heart transplantation. Methods: All patients received mild hypothermia and high flow rate perfusion. Effective strategies were taken to protect myocardium, lung, kidney, and blood conservation. The donor hearts were arrested with aorto perfusion using 1 000 ml St. Thomas solution at 4°C, perfused with 1 000 ml University of Wiscosin (UW) solution or Histidin-Tryptophan-Ketoglutarat (HTK) solution at 4°C, and then preserved in ice saline. Ice mud was covered on the donor heart during anastomosis. Low potassium cardioplegia solution was perfused before the unclamping of aorta. Results: The CPB time was (165.2 ± 22.8) min, the warm ischemia time was (7.7 ± 1.7) min, and the cold ischemia time was (142.4 ± 11.5) min. Heart beats was automatically recovered in 10 patients, and was recovered upon defibrillation in 5 patients. Left ventricular ejection fractions were (64.1 ± 4.6)% after one month. All patients survived. Conclusion: Proper CPB management and effective donor heart protection are essential to guarantee the success of heart transplantations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 228-231 |
| Number of pages | 4 |
| Journal | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae |
| Volume | 29 |
| Issue number | 2 |
| State | Published - Apr 2007 |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Experiences of cardiopulmonary bypass for heart transplantation. / Hei, Fei Long; Wang, Shigang; Long, Cun.
In: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, Vol. 29, No. 2, 04.2007, p. 228-231.Research output: Contribution to journal › Article
TY - JOUR
T1 - Experiences of cardiopulmonary bypass for heart transplantation
AU - Hei, Fei Long
AU - Wang, Shigang
AU - Long, Cun
PY - 2007/4
Y1 - 2007/4
N2 - Objective: To summarize the experiences of cardiopulmonary bypass (CPB) techniques in 15 patients of orthotopic heart transplantation. Methods: All patients received mild hypothermia and high flow rate perfusion. Effective strategies were taken to protect myocardium, lung, kidney, and blood conservation. The donor hearts were arrested with aorto perfusion using 1 000 ml St. Thomas solution at 4°C, perfused with 1 000 ml University of Wiscosin (UW) solution or Histidin-Tryptophan-Ketoglutarat (HTK) solution at 4°C, and then preserved in ice saline. Ice mud was covered on the donor heart during anastomosis. Low potassium cardioplegia solution was perfused before the unclamping of aorta. Results: The CPB time was (165.2 ± 22.8) min, the warm ischemia time was (7.7 ± 1.7) min, and the cold ischemia time was (142.4 ± 11.5) min. Heart beats was automatically recovered in 10 patients, and was recovered upon defibrillation in 5 patients. Left ventricular ejection fractions were (64.1 ± 4.6)% after one month. All patients survived. Conclusion: Proper CPB management and effective donor heart protection are essential to guarantee the success of heart transplantations.
AB - Objective: To summarize the experiences of cardiopulmonary bypass (CPB) techniques in 15 patients of orthotopic heart transplantation. Methods: All patients received mild hypothermia and high flow rate perfusion. Effective strategies were taken to protect myocardium, lung, kidney, and blood conservation. The donor hearts were arrested with aorto perfusion using 1 000 ml St. Thomas solution at 4°C, perfused with 1 000 ml University of Wiscosin (UW) solution or Histidin-Tryptophan-Ketoglutarat (HTK) solution at 4°C, and then preserved in ice saline. Ice mud was covered on the donor heart during anastomosis. Low potassium cardioplegia solution was perfused before the unclamping of aorta. Results: The CPB time was (165.2 ± 22.8) min, the warm ischemia time was (7.7 ± 1.7) min, and the cold ischemia time was (142.4 ± 11.5) min. Heart beats was automatically recovered in 10 patients, and was recovered upon defibrillation in 5 patients. Left ventricular ejection fractions were (64.1 ± 4.6)% after one month. All patients survived. Conclusion: Proper CPB management and effective donor heart protection are essential to guarantee the success of heart transplantations.
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M3 - Article
VL - 29
SP - 228
EP - 231
JO - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
JF - Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
SN - 1000-503X
IS - 2
ER -