Experimental Bovine Respiratory Tract Disease with Haemophilus somnus

L. N.D. Potgieter, R. G. Helman, W. Greene, M. A. Breider, E. T. Thurber, R. H. Peetz

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Abstract

Eight calves were inoculated into the bronchus with H. somnus. Thirteen calves were inoculated with bovine respiratory syncytial virus (BRSV) and 8 days later with H. somnus. All calves developed necrotizing, suppurative, lobular bronchopneumonia and pleuritis. Clinical signs of disease and pneumonic lesions were significantly more severe in calves that were sequentially inoculated with BRSV followed by H. somnus. Pneumonic lesions in the inoculated calves were similar to those described for naturally occurring H. somnus-associated respiratory tract disease. Control calves inoculated with BRSV alone or sham-inoculated with medium did not develop clinical signs of respiratory tract disease. The BRSV-inoculated control calves developed minimal pneumonic lesions.

Original languageEnglish (US)
Pages (from-to)124-130
Number of pages7
JournalVeterinary Pathology
Volume25
Issue number2
DOIs
StatePublished - Mar 1988

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All Science Journal Classification (ASJC) codes

  • veterinary(all)

Cite this

Potgieter, L. N. D., Helman, R. G., Greene, W., Breider, M. A., Thurber, E. T., & Peetz, R. H. (1988). Experimental Bovine Respiratory Tract Disease with Haemophilus somnus. Veterinary Pathology, 25(2), 124-130. https://doi.org/10.1177/030098588802500204