Experimental Bovine Respiratory Tract Disease with Haemophilus somnus

L. N.D. Potgieter, R. G. Helman, W. Greene, M. A. Breider, E. T. Thurber, R. H. Peetz

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Eight calves were inoculated into the bronchus with H. somnus. Thirteen calves were inoculated with bovine respiratory syncytial virus (BRSV) and 8 days later with H. somnus. All calves developed necrotizing, suppurative, lobular bronchopneumonia and pleuritis. Clinical signs of disease and pneumonic lesions were significantly more severe in calves that were sequentially inoculated with BRSV followed by H. somnus. Pneumonic lesions in the inoculated calves were similar to those described for naturally occurring H. somnus-associated respiratory tract disease. Control calves inoculated with BRSV alone or sham-inoculated with medium did not develop clinical signs of respiratory tract disease. The BRSV-inoculated control calves developed minimal pneumonic lesions.

Original languageEnglish (US)
Pages (from-to)124-130
Number of pages7
JournalVeterinary Pathology
Volume25
Issue number2
DOIs
StatePublished - Mar 1988

All Science Journal Classification (ASJC) codes

  • veterinary(all)

Fingerprint Dive into the research topics of 'Experimental Bovine Respiratory Tract Disease with Haemophilus somnus'. Together they form a unique fingerprint.

Cite this