Experimental Evaluation of a Surface Charge Method for Computing the Induced Magnetic Field in Trabecular Bone

Scott N. Hwang, Felix W. Wehrli

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The magnetic field induced in the pores of trabecular bone as a result of the susceptibility difference between bone and bone marrow was computed with the aid of magnetic surface charge models generated from images of trabecular bone specimens acquired at 78 and 63 μm resolution. The predicted field was compared with the values derived from 2D and 3D field maps obtained by echo-offset imaging techniques and excellent agreement was found between the two methods. Finally, from the slopes of regression between the experimental and computed fields, the absolute susceptibility of bone was nondestructively determined as -11.0 × 10-6 (MKS), which is in close agreement with a reported value of -11.3 × 10-6 obtained with powdered bone by means of a spectroscopic susceptibility matching technique (J. A. Hopkins and F. W. Wehrli, Magn. Reson. Med. 37, 494-500 (1997)).

Original languageEnglish (US)
Pages (from-to)35-45
Number of pages11
JournalJournal of Magnetic Resonance
Issue number1
StatePublished - Jul 1999

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics

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