Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil

Jay H. Post, John F. Cardella, Ronald P. Wilson, James W. Griffith, Preston S. Fox, Peter N. Waybill, James R. Hills

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

PURPOSE: Investigation of a technique for nonsurgical female sterilization. MATERIALS AND METHODS: A custom designed platinum microcoil with Dacron fibers was placed unilaterally into a fallopian tube and uterine horn of 10 rabbits after transcervical selective tubal catheterization with use of fluoroscopic guidance. The contralateral uterus and fallopian tube served as controls. After the rabbits were bred, pregnancy was determined by palpation and confirmed at autopsy. Postmortem histopathologic evaluation of uteri and fallopian tubes was performed. RESULTS: Nine of the 10 rabbits became pregnant. None of the animals had embryos on the microcoil side. Nine rabbits had a total of 45 embryos on the control side. One animal failed to become pregnant on either side. The microcoil remained in good position in all 10 rabbits. There was a microcoil-associated, mild inflammatory tissue response in the uteri and fallopian tubes. CONCLUSION: A platinum occlusion microcoil placed in a uterotubal location has potential as a means for nonsurgical female sterilization.

Original languageEnglish (US)
Pages (from-to)113-118
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume8
Issue number1
DOIs
StatePublished - Jan 1 1997

Fingerprint

Platinum
Fallopian Tubes
Rabbits
Reproductive Sterilization
Uterus
Embryonic Structures
Polyethylene Terephthalates
Palpation
Catheterization
Autopsy
Pregnancy

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Post, Jay H. ; Cardella, John F. ; Wilson, Ronald P. ; Griffith, James W. ; Fox, Preston S. ; Waybill, Peter N. ; Hills, James R. / Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil. In: Journal of Vascular and Interventional Radiology. 1997 ; Vol. 8, No. 1. pp. 113-118.
@article{4ff03bf193a44adc9a345af106304601,
title = "Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil",
abstract = "PURPOSE: Investigation of a technique for nonsurgical female sterilization. MATERIALS AND METHODS: A custom designed platinum microcoil with Dacron fibers was placed unilaterally into a fallopian tube and uterine horn of 10 rabbits after transcervical selective tubal catheterization with use of fluoroscopic guidance. The contralateral uterus and fallopian tube served as controls. After the rabbits were bred, pregnancy was determined by palpation and confirmed at autopsy. Postmortem histopathologic evaluation of uteri and fallopian tubes was performed. RESULTS: Nine of the 10 rabbits became pregnant. None of the animals had embryos on the microcoil side. Nine rabbits had a total of 45 embryos on the control side. One animal failed to become pregnant on either side. The microcoil remained in good position in all 10 rabbits. There was a microcoil-associated, mild inflammatory tissue response in the uteri and fallopian tubes. CONCLUSION: A platinum occlusion microcoil placed in a uterotubal location has potential as a means for nonsurgical female sterilization.",
author = "Post, {Jay H.} and Cardella, {John F.} and Wilson, {Ronald P.} and Griffith, {James W.} and Fox, {Preston S.} and Waybill, {Peter N.} and Hills, {James R.}",
year = "1997",
month = "1",
day = "1",
doi = "10.1016/S1051-0443(97)70525-6",
language = "English (US)",
volume = "8",
pages = "113--118",
journal = "Journal of Vascular and Interventional Radiology",
issn = "1051-0443",
publisher = "Elsevier Inc.",
number = "1",

}

Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil. / Post, Jay H.; Cardella, John F.; Wilson, Ronald P.; Griffith, James W.; Fox, Preston S.; Waybill, Peter N.; Hills, James R.

In: Journal of Vascular and Interventional Radiology, Vol. 8, No. 1, 01.01.1997, p. 113-118.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Experimental nonsurgical transcervical sterilization with a custom-designed platinum microcoil

AU - Post, Jay H.

AU - Cardella, John F.

AU - Wilson, Ronald P.

AU - Griffith, James W.

AU - Fox, Preston S.

AU - Waybill, Peter N.

AU - Hills, James R.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - PURPOSE: Investigation of a technique for nonsurgical female sterilization. MATERIALS AND METHODS: A custom designed platinum microcoil with Dacron fibers was placed unilaterally into a fallopian tube and uterine horn of 10 rabbits after transcervical selective tubal catheterization with use of fluoroscopic guidance. The contralateral uterus and fallopian tube served as controls. After the rabbits were bred, pregnancy was determined by palpation and confirmed at autopsy. Postmortem histopathologic evaluation of uteri and fallopian tubes was performed. RESULTS: Nine of the 10 rabbits became pregnant. None of the animals had embryos on the microcoil side. Nine rabbits had a total of 45 embryos on the control side. One animal failed to become pregnant on either side. The microcoil remained in good position in all 10 rabbits. There was a microcoil-associated, mild inflammatory tissue response in the uteri and fallopian tubes. CONCLUSION: A platinum occlusion microcoil placed in a uterotubal location has potential as a means for nonsurgical female sterilization.

AB - PURPOSE: Investigation of a technique for nonsurgical female sterilization. MATERIALS AND METHODS: A custom designed platinum microcoil with Dacron fibers was placed unilaterally into a fallopian tube and uterine horn of 10 rabbits after transcervical selective tubal catheterization with use of fluoroscopic guidance. The contralateral uterus and fallopian tube served as controls. After the rabbits were bred, pregnancy was determined by palpation and confirmed at autopsy. Postmortem histopathologic evaluation of uteri and fallopian tubes was performed. RESULTS: Nine of the 10 rabbits became pregnant. None of the animals had embryos on the microcoil side. Nine rabbits had a total of 45 embryos on the control side. One animal failed to become pregnant on either side. The microcoil remained in good position in all 10 rabbits. There was a microcoil-associated, mild inflammatory tissue response in the uteri and fallopian tubes. CONCLUSION: A platinum occlusion microcoil placed in a uterotubal location has potential as a means for nonsurgical female sterilization.

UR - http://www.scopus.com/inward/record.url?scp=0030729634&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030729634&partnerID=8YFLogxK

U2 - 10.1016/S1051-0443(97)70525-6

DO - 10.1016/S1051-0443(97)70525-6

M3 - Article

C2 - 9025049

AN - SCOPUS:0030729634

VL - 8

SP - 113

EP - 118

JO - Journal of Vascular and Interventional Radiology

JF - Journal of Vascular and Interventional Radiology

SN - 1051-0443

IS - 1

ER -