Experiments in virtual-endoscopic guidance of bronchoscopy

J. P. Helferty, A. J. Sherbondy, A. P. Kiraly, J. Z. Turlington, E. A. Hoffman, G. McLennan, William Evan Higgins

Research output: Contribution to journalConference article

8 Scopus citations


Transbronchial needle biopsy is a common procedure for early detection of lung cancer. In practice, accurate results are difficult to obtain, since the bronchoscopy procedure requires a blind puncture into a region hidden behind the airway walls. This paper presents an image-guided endoscopy system for procedure preplanning and for guidance during bronchoscopy. Before the bronchoscopy, a 3D CT scan is analyzed to define guidance paths through the major airways to suspect biopsy sites. During subsequent bronchoscopy, the paths give the physician step-by-step guidance to each suspect site location. At a suspect site, a virtual CT image is registered to the bronchoscopic video. Then, the predefined biopsy site, from the prior CT analysis, is rendered onto the registered video. This gives the physician a reference for performing the needle biopsy. This paper focuses on our recent experiments with this system. These experiments involve a rubber phantom model of the human airway tree and in vivo animal tests. The experiments demonstrate the promise of our approach.

Original languageEnglish (US)
Pages (from-to)111-121
Number of pages11
JournalProceedings of SPIE - The International Society for Optical Engineering
StatePublished - Jan 1 2001
EventMedical Imaging 2001: Physiology and Function from Multidimensional Images - Sandiego, CA, United States
Duration: Feb 18 2001Feb 20 2001


All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

Helferty, J. P., Sherbondy, A. J., Kiraly, A. P., Turlington, J. Z., Hoffman, E. A., McLennan, G., & Higgins, W. E. (2001). Experiments in virtual-endoscopic guidance of bronchoscopy. Proceedings of SPIE - The International Society for Optical Engineering, 4321, 111-121. https://doi.org/10.1117/12.428127