Exploratory research synthesis

Methodological Considerations for Addressing Limitations in Data Quality

William H. Yeation, John C. Langenbrunner, Joshua Morrison Smyth, Paul M. Wortman

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Exploratory meta-analysis or research synthesis has been advocated as a way of developing important hypotheses for further study. An exploratory research synthesis was conducted on the carotid endarterectomy (CE) literature to illustrate this method. The CE scientific literature is similar to that of many other new medical interventions because it contains numerous limitations to data quality. Exploratory research synthesis of such literature necessitates a number of methodological and statistical considerations to address these limitations, including the problems of missing data, appropriate unit of analysis, nonnormal distribution of outcomes, and lack of controlled studies. Strengths and limitations of the exploratory research synthesis approach are discussed within the context of public policy decisions for assessing medical technologies.

Original languageEnglish (US)
Pages (from-to)283-303
Number of pages21
JournalEvaluation & the Health Professions
Volume18
Issue number3
DOIs
StatePublished - Jan 1 1995

Fingerprint

Carotid Endarterectomy
Research
Literature
Public Policy
Meta-Analysis
Technology
Data Accuracy

All Science Journal Classification (ASJC) codes

  • Health Policy

Cite this

@article{983565f409104617adf99b7cb60c58be,
title = "Exploratory research synthesis: Methodological Considerations for Addressing Limitations in Data Quality",
abstract = "Exploratory meta-analysis or research synthesis has been advocated as a way of developing important hypotheses for further study. An exploratory research synthesis was conducted on the carotid endarterectomy (CE) literature to illustrate this method. The CE scientific literature is similar to that of many other new medical interventions because it contains numerous limitations to data quality. Exploratory research synthesis of such literature necessitates a number of methodological and statistical considerations to address these limitations, including the problems of missing data, appropriate unit of analysis, nonnormal distribution of outcomes, and lack of controlled studies. Strengths and limitations of the exploratory research synthesis approach are discussed within the context of public policy decisions for assessing medical technologies.",
author = "Yeation, {William H.} and Langenbrunner, {John C.} and Smyth, {Joshua Morrison} and Wortman, {Paul M.}",
year = "1995",
month = "1",
day = "1",
doi = "10.1177/016327879501800304",
language = "English (US)",
volume = "18",
pages = "283--303",
journal = "Evaluation and the Health Professions",
issn = "0163-2787",
publisher = "SAGE Publications Inc.",
number = "3",

}

Exploratory research synthesis : Methodological Considerations for Addressing Limitations in Data Quality. / Yeation, William H.; Langenbrunner, John C.; Smyth, Joshua Morrison; Wortman, Paul M.

In: Evaluation & the Health Professions, Vol. 18, No. 3, 01.01.1995, p. 283-303.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Exploratory research synthesis

T2 - Methodological Considerations for Addressing Limitations in Data Quality

AU - Yeation, William H.

AU - Langenbrunner, John C.

AU - Smyth, Joshua Morrison

AU - Wortman, Paul M.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Exploratory meta-analysis or research synthesis has been advocated as a way of developing important hypotheses for further study. An exploratory research synthesis was conducted on the carotid endarterectomy (CE) literature to illustrate this method. The CE scientific literature is similar to that of many other new medical interventions because it contains numerous limitations to data quality. Exploratory research synthesis of such literature necessitates a number of methodological and statistical considerations to address these limitations, including the problems of missing data, appropriate unit of analysis, nonnormal distribution of outcomes, and lack of controlled studies. Strengths and limitations of the exploratory research synthesis approach are discussed within the context of public policy decisions for assessing medical technologies.

AB - Exploratory meta-analysis or research synthesis has been advocated as a way of developing important hypotheses for further study. An exploratory research synthesis was conducted on the carotid endarterectomy (CE) literature to illustrate this method. The CE scientific literature is similar to that of many other new medical interventions because it contains numerous limitations to data quality. Exploratory research synthesis of such literature necessitates a number of methodological and statistical considerations to address these limitations, including the problems of missing data, appropriate unit of analysis, nonnormal distribution of outcomes, and lack of controlled studies. Strengths and limitations of the exploratory research synthesis approach are discussed within the context of public policy decisions for assessing medical technologies.

UR - http://www.scopus.com/inward/record.url?scp=0029086184&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029086184&partnerID=8YFLogxK

U2 - 10.1177/016327879501800304

DO - 10.1177/016327879501800304

M3 - Article

VL - 18

SP - 283

EP - 303

JO - Evaluation and the Health Professions

JF - Evaluation and the Health Professions

SN - 0163-2787

IS - 3

ER -