Exploring the underlying genetics of craniofacial morphology through various sources of knowledge

Jasmien Roosenboom, Greet Hens, Brooke C. Mattern, Mark Shriver, Peter Claes

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.

Original languageEnglish (US)
Article number3054578
JournalBioMed Research International
Volume2016
DOIs
StatePublished - Jan 1 2016

Fingerprint

Genes
Health
Phenotype
Genetics
DNA

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Roosenboom, Jasmien ; Hens, Greet ; Mattern, Brooke C. ; Shriver, Mark ; Claes, Peter. / Exploring the underlying genetics of craniofacial morphology through various sources of knowledge. In: BioMed Research International. 2016 ; Vol. 2016.
@article{eed1871368ff48608f4c0f74ab0c1242,
title = "Exploring the underlying genetics of craniofacial morphology through various sources of knowledge",
abstract = "The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.",
author = "Jasmien Roosenboom and Greet Hens and Mattern, {Brooke C.} and Mark Shriver and Peter Claes",
year = "2016",
month = "1",
day = "1",
doi = "10.1155/2016/3054578",
language = "English (US)",
volume = "2016",
journal = "BioMed Research International",
issn = "2314-6133",
publisher = "Hindawi Publishing Corporation",

}

Exploring the underlying genetics of craniofacial morphology through various sources of knowledge. / Roosenboom, Jasmien; Hens, Greet; Mattern, Brooke C.; Shriver, Mark; Claes, Peter.

In: BioMed Research International, Vol. 2016, 3054578, 01.01.2016.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Exploring the underlying genetics of craniofacial morphology through various sources of knowledge

AU - Roosenboom, Jasmien

AU - Hens, Greet

AU - Mattern, Brooke C.

AU - Shriver, Mark

AU - Claes, Peter

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.

AB - The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.

UR - http://www.scopus.com/inward/record.url?scp=85008686509&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85008686509&partnerID=8YFLogxK

U2 - 10.1155/2016/3054578

DO - 10.1155/2016/3054578

M3 - Review article

C2 - 28053980

AN - SCOPUS:85008686509

VL - 2016

JO - BioMed Research International

JF - BioMed Research International

SN - 2314-6133

M1 - 3054578

ER -