Exploring the underlying genetics of craniofacial morphology through various sources of knowledge

Jasmien Roosenboom, Greet Hens, Brooke C. Mattern, Mark D. Shriver, Peter Claes

Research output: Contribution to journalReview article

12 Scopus citations

Abstract

The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.

Original languageEnglish (US)
Article number3054578
JournalBioMed Research International
Volume2016
DOIs
StatePublished - 2016

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

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